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Journal of Medicinal Chemistry|November 14, 2018
Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent InhibitorsAgustin Casimiro-Garcia, John I Trujillo, Felix Vajdos, et al.Journal of Medicinal Chemistry|August 25, 2007
Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitrilesNeal Green, Yonghan Hu, Kristin Janz, et al.Journal of Medicinal Chemistry|October 24, 2007
Discovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonistDerek C Cole, Joseph R Stock, William J Lennox, et al.Journal of Medicinal Chemistry|August 21, 2007
Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding siteDouglas P Wilson, Zhao-Kui Wan, Wei-Xin Xu, et al.Journal of Medicinal Chemistry|February 1, 2017
Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in HumansAtli Thorarensen, Martin E Dowty, Mary Ellen Banker, et al.ACS Chemical Biology|October 30, 2016
Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective InhibitionJean-Baptiste Telliez, Martin E Dowty, Lu Wang, et al.Pageof 4