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Biorxiv : the Preprint Server for Biology
|
March 31, 2025
The <i>Endo-GeneScreen</i> Platform Identifies Drug-Like Probes that Regulate Endogenous Protein Levels within Physiological Contexts
Preston Samowitz, Laszlo Radnai, Thomas Vaissiere, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
August 1, 2020
Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening
Yuka Otsuka, Michael V Airola, Yong-Mi Choi, et al.
Nature Communications
|
December 9, 2025
The Endo-GeneScreen platform identifies drug-like probes that regulate endogenous protein levels within physiological contexts
Preston Samowitz, Laszlo Radnai, Thomas Vaissiere, et al.
Journal of Biomolecular Screening
|
April 17, 2015
Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4)
Emery Smith, Peter Chase, Colleen M Niswender, et al.
Cancers
|
July 14, 2023
In Vitro and In Vivo Drug-Response Profiling Using Patient-Derived High-Grade Glioma
Robin G Rajan, Virneliz Fernandez-Vega, Jantzen Sperry, et al.
Journal of Biomolecular Screening
|
August 29, 2014
Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening
Laura Pedró-Rosa, Frederick S Buckner, Ranae M Ranade, et al.
Science Advances
|
June 5, 2020
Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
Leiming Wang, Chiang-Min Cheng, Jun Qin, et al.
Molecular Neuropsychiatry
|
March 30, 2018
Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders
Timothy P Spicer, Christopher Hubbs, Thomas Vaissiere, et al.
Molecular Oncology
|
June 14, 2020
An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer
Chun-Hao Pan, Yuka Otsuka, BanuPriya Sridharan, et al.
Mbio
|
April 26, 2022
Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M<sup>pro</sup>/3CL<sup>pro</sup> in Living Cells
Seyed Arad Moghadasi, Morgan A Esler, Yuka Otsuka, et al.
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Search research articles
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Showing results (81-90 of 103) with videos related to
Sort By:
Page
of 11
Biorxiv : the Preprint Server for Biology
|
March 31, 2025
The <i>Endo-GeneScreen</i> Platform Identifies Drug-Like Probes that Regulate Endogenous Protein Levels within Physiological Contexts
Preston Samowitz, Laszlo Radnai, Thomas Vaissiere, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
August 1, 2020
Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening
Yuka Otsuka, Michael V Airola, Yong-Mi Choi, et al.
Nature Communications
|
December 9, 2025
The Endo-GeneScreen platform identifies drug-like probes that regulate endogenous protein levels within physiological contexts
Preston Samowitz, Laszlo Radnai, Thomas Vaissiere, et al.
Journal of Biomolecular Screening
|
April 17, 2015
Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4)
Emery Smith, Peter Chase, Colleen M Niswender, et al.
Cancers
|
July 14, 2023
In Vitro and In Vivo Drug-Response Profiling Using Patient-Derived High-Grade Glioma
Robin G Rajan, Virneliz Fernandez-Vega, Jantzen Sperry, et al.
Journal of Biomolecular Screening
|
August 29, 2014
Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening
Laura Pedró-Rosa, Frederick S Buckner, Ranae M Ranade, et al.
Science Advances
|
June 5, 2020
Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
Leiming Wang, Chiang-Min Cheng, Jun Qin, et al.
Molecular Neuropsychiatry
|
March 30, 2018
Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders
Timothy P Spicer, Christopher Hubbs, Thomas Vaissiere, et al.
Molecular Oncology
|
June 14, 2020
An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer
Chun-Hao Pan, Yuka Otsuka, BanuPriya Sridharan, et al.
Mbio
|
April 26, 2022
Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M<sup>pro</sup>/3CL<sup>pro</sup> in Living Cells
Seyed Arad Moghadasi, Morgan A Esler, Yuka Otsuka, et al.
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of 11