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American Journal of Respiratory and Critical Care Medicine|July 5, 2016
Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary EmphysemaSaleela M Ruwanpura, Louise McLeod, Lovisa F Dousha, et al.Journal of Immunology (Baltimore, Md. : 1950)|June 5, 2023
Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like RetroelementsDavid Millrine, Ana Cardus Figueras, Javier Uceda Fernandez, et al.Proceedings of the National Academy of Sciences of the United States of America|August 29, 2022
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysemaSaleela M Ruwanpura, Louise McLeod, Lovisa F Dousha, et al.Nature Communications|February 7, 2026
Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancerYu C J Chey, Bassam Kashgari, Louise McLeod, et al.EMBO Molecular Medicine|March 6, 2019
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancerMohamed I Saad, Sultan Alhayyani, Louise McLeod, et al.Immunity|January 14, 2014
Interleukin-6 signaling drives fibrosis in unresolved inflammationCeri A Fielding, Gareth W Jones, Rachel M McLoughlin, et al.Pageof 3