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Scientific Reports|November 4, 2025
Prognostic prediction in soft-tissue sarcomas using deep learning and digital pathology of tumor and margin areasAudrey Michot, Van-Linh Le, Jean-Michel Coindre, et al.
Cell Reports. Medicine|February 5, 2025
Spatially resolved transcriptomics reveal the determinants of primary resistance to immunotherapy in NSCLC with mature tertiary lymphoid structuresFlorent Peyraud, Jean-Philippe Guégan, Christophe Rey, et al.
Nature Cancer|April 9, 2025
Regorafenib plus avelumab in advanced gastroenteropancreatic neuroendocrine neoplasms: a phase 2 trial and correlative analysisSophie Cousin, Jean-Philippe Guégan, Lola Jade Palmieri, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology|February 21, 2023
Standardized Pathology Screening of Mature Tertiary Lymphoid Structures in CancersLucile Vanhersecke, Antoine Bougouin, Amandine Crombé, et al.
Molecular Cancer|September 13, 2024
Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomicsSophie Cousin, Jean-Philippe Guégan, Kohei Shitara, et al.
Cell Reports. Medicine|November 26, 2024
Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy responseJean-Philippe Guégan, Florent Peyraud, Bérengère Dadone-Montaudie, et al.
Cancer Cell|July 9, 2026
GABA promotes resistance to immunotherapy in patients with TLS-positive tumorsIsaias Hernández-Verdin, Anne Calvez, Cheng-Ming Sun, et al.
Nature Cancer|February 4, 2022
Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expressionLucile Vanhersecke, Maxime Brunet, Jean-Philippe Guégan, et al.
Cancer Research|June 8, 2026
Deep Learning Predicts Mutations and Outcomes in Gastrointestinal Stromal Tumors from Whole-Slide ImagesArianna Bonetti, Van-Linh Le, Zunamys I Carrero, et al.
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