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Nature Communications|June 21, 2020
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologuesKatherine A Davies, Cheree Fitzgibbon, Samuel N Young, et al.Nature Communications|June 23, 2018
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosisEmma J Petrie, Jarrod J Sandow, Annette V Jacobsen, et al.Cell Reports|September 26, 2019
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3Emma J Petrie, Jarrod J Sandow, Wil I L Lehmann, et al.ACS Chemical Biology|September 9, 2020
Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the PathwayCatia L Pierotti, Maria C Tanzer, Annette V Jacobsen, et al.Nature Communications|June 8, 2021
Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearanceLaura Ramos Garcia, Tencho Tenev, Richard Newman, et al.Pageof 2