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Journal of Chemical Information and Modeling
|
September 30, 2010
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicity
George Papadatos, Muhammad Alkarouri, Valerie J Gillet, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 25, 2018
Novel M<sub>4</sub> positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands
Michael S Poslusney, James M Salovich, Michael R Wood, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 22, 2017
Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl)piperazin-1-yl)-6-(piperidin-1-yl)pyridazines as novel, CNS penetrant pan-muscarinic antagonists
Aaron M Bender, Rebecca L Weiner, Vincent B Luscombe, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2017
Discovery of a novel, CNS penetrant M<sub>4</sub> PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core
Blake R Bewley, Paul K Spearing, Rebecca L Weiner, et al.
Epigenetics
|
March 2, 2016
Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer
Mark O Kitchen, Richard T Bryan, Richard D Emes, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 18, 2017
Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M<sub>4</sub> positive allosteric modulator (PAM) chemotype via scaffold hopping
Madeline F Long, Julie L Engers, Sichen Chang, et al.
Genome Research
|
April 10, 2010
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities
Arttu Jolma, Teemu Kivioja, Jarkko Toivonen, et al.
Ebiomedicine
|
June 23, 2016
Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications
George D Cresswell, John R Apps, Tasnim Chagtai, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 1, 2019
Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M<sub>4</sub> positive allosteric modulator (PAM) chemotype
Kayla J Temple, Julie L Engers, Madeline F Long, et al.
Nature
|
January 25, 2023
Annelid functional genomics reveal the origins of bilaterian life cycles
Francisco M Martín-Zamora, Yan Liang, Kero Guynes, et al.
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Search research articles
Search
Showing results (651-660 of 713) with videos related to
Sort By:
Page
of 72
Journal of Chemical Information and Modeling
|
September 30, 2010
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicity
George Papadatos, Muhammad Alkarouri, Valerie J Gillet, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 25, 2018
Novel M<sub>4</sub> positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands
Michael S Poslusney, James M Salovich, Michael R Wood, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 22, 2017
Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl)piperazin-1-yl)-6-(piperidin-1-yl)pyridazines as novel, CNS penetrant pan-muscarinic antagonists
Aaron M Bender, Rebecca L Weiner, Vincent B Luscombe, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2017
Discovery of a novel, CNS penetrant M<sub>4</sub> PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core
Blake R Bewley, Paul K Spearing, Rebecca L Weiner, et al.
Epigenetics
|
March 2, 2016
Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer
Mark O Kitchen, Richard T Bryan, Richard D Emes, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 18, 2017
Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M<sub>4</sub> positive allosteric modulator (PAM) chemotype via scaffold hopping
Madeline F Long, Julie L Engers, Sichen Chang, et al.
Genome Research
|
April 10, 2010
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities
Arttu Jolma, Teemu Kivioja, Jarkko Toivonen, et al.
Ebiomedicine
|
June 23, 2016
Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications
George D Cresswell, John R Apps, Tasnim Chagtai, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 1, 2019
Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M<sub>4</sub> positive allosteric modulator (PAM) chemotype
Kayla J Temple, Julie L Engers, Madeline F Long, et al.
Nature
|
January 25, 2023
Annelid functional genomics reveal the origins of bilaterian life cycles
Francisco M Martín-Zamora, Yan Liang, Kero Guynes, et al.
Page
of 72