Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Luscombe

Showing results (691-700 of 713) with videos related to

Pageof 72
Sort By:
ACS Chemical Neuroscience|September 24, 2024
Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)Julie L Engers, Logan A Baker, Sichen Chang, et al.
BMJ Open|April 29, 2026
The GRACE video-telehealth project protocol: a mixed-methods study to improve quality, safety and acceptability of video-telehealth in Australian general practice and residential aged careAnn Carrigan, Melissa T Baysari, Georgina Luscombe, et al.
ACS Chemical Neuroscience|December 22, 2016
Diverse Effects on M<sub>1</sub> Signaling and Adverse Effect Liability within a Series of M<sub>1</sub> Ago-PAMsJerri M Rook, Masahito Abe, Hyekyung P Cho, et al.
Journal of Bacteriology|April 1, 2008
Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motilityMelanie M Pearson, Mohammed Sebaihia, Carol Churcher, et al.
Bioorganic & Medicinal Chemistry Letters|November 2, 2017
Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amidesJames C Tarr, Michael R Wood, Meredith J Noetzel, et al.
Genome Research|March 11, 2015
The pluripotent regulatory circuitry connecting promoters to their long-range interacting elementsStefan Schoenfelder, Mayra Furlan-Magaril, Borbala Mifsud, et al.
Bioorganic & Medicinal Chemistry Letters|December 13, 2016
Challenges in the development of an M<sub>4</sub> PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogsMichael R Wood, Meredith J Noetzel, Michael S Poslusney, et al.
Journal of Medicinal Chemistry|May 23, 2017
Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical EvaluationAndrew S Felts, Alice L Rodriguez, Anna L Blobaum, et al.
ACS Chemical Neuroscience|April 22, 2018
Discovery and Optimization of Potent and CNS Penetrant M<sub>5</sub>-Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide ScaffoldAaron M Bender, Hyekyung P Cho, Kellie D Nance, et al.
Nature Communications|July 2, 2025
Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weightMichaela Gregorova, Marianna Santopaolo, Lucy C Garner, et al.
Pageof 72

Showing results (691-700 of 713) with videos related to

Sort By:
Pageof 72
ACS Chemical Neuroscience|September 24, 2024
Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)Julie L Engers, Logan A Baker, Sichen Chang, et al.
BMJ Open|April 29, 2026
The GRACE video-telehealth project protocol: a mixed-methods study to improve quality, safety and acceptability of video-telehealth in Australian general practice and residential aged careAnn Carrigan, Melissa T Baysari, Georgina Luscombe, et al.
ACS Chemical Neuroscience|December 22, 2016
Diverse Effects on M<sub>1</sub> Signaling and Adverse Effect Liability within a Series of M<sub>1</sub> Ago-PAMsJerri M Rook, Masahito Abe, Hyekyung P Cho, et al.
Journal of Bacteriology|April 1, 2008
Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motilityMelanie M Pearson, Mohammed Sebaihia, Carol Churcher, et al.
Bioorganic & Medicinal Chemistry Letters|November 2, 2017
Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amidesJames C Tarr, Michael R Wood, Meredith J Noetzel, et al.
Genome Research|March 11, 2015
The pluripotent regulatory circuitry connecting promoters to their long-range interacting elementsStefan Schoenfelder, Mayra Furlan-Magaril, Borbala Mifsud, et al.
Bioorganic & Medicinal Chemistry Letters|December 13, 2016
Challenges in the development of an M<sub>4</sub> PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogsMichael R Wood, Meredith J Noetzel, Michael S Poslusney, et al.
Journal of Medicinal Chemistry|May 23, 2017
Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical EvaluationAndrew S Felts, Alice L Rodriguez, Anna L Blobaum, et al.
ACS Chemical Neuroscience|April 22, 2018
Discovery and Optimization of Potent and CNS Penetrant M<sub>5</sub>-Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide ScaffoldAaron M Bender, Hyekyung P Cho, Kellie D Nance, et al.
Nature Communications|July 2, 2025
Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weightMichaela Gregorova, Marianna Santopaolo, Lucy C Garner, et al.
Pageof 72