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Expert Opinion on Therapeutic Patents|January 10, 2026
A patent review of DNA polymerase theta (Polθ) targeted therapies (2019-2025)Luyu Ma, Mingjin Luo, Hua Xiang, et al.Genomics, Proteomics & Bioinformatics|January 1, 2022
RegVar: Tissue-specific Prioritization of Non-coding Regulatory VariantsHao Lu, Luyu Ma, Cheng Quan, et al.Frontiers in Genetics|March 27, 2026
Potential effects on the signaling network mediated by overexpression of the vitronectin gene in Hu sheep ruminal epithelial cells using multi-omics analysisBingqian Zhong, Luyu Ma, Hua Ni, et al.European Journal of Medicinal Chemistry|October 5, 2021
Development of novel tetrahydroisoquinoline-hydroxamate conjugates as potent dual SERDs/HDAC inhibitors for the treatment of breast cancerGuoshun Luo, Xin Lin, Shengnan Ren, et al.Biochemical and Biophysical Research Communications|July 31, 2025
Integrating network pharmacology and transcriptomics to reveal the anti-hepatocellular carcinoma effects of Nigella B via activation of the P38MAPK pathwayXiubin Jia, Zhao Wang, Runze Zhang, et al.Journal of Medicinal Chemistry|February 20, 2024
Discovery and Proof of Concept of Potent Dual Polθ/PARP Inhibitors for Efficient Treatment of Homologous Recombination-Deficient TumorsLuyu Ma, Wei Chen, Ming Yang, et al.Proteomics|October 30, 2013
Proteomics analysis of UV-irradiated Lonicera japonica Thunb. with bioactive metabolites enhancementLin Zhang, Ximin Li, Wen Zheng, et al.European Journal of Medicinal Chemistry|May 1, 2026
Discovery of an orally bioavailable selenium-containing Polθ inhibitor with a dual mechanism of DNA damage and immune activation for HR-deficient cancersLuyu Ma, Mingjin Luo, Xiangchi Liu, et al.Frontiers in Cellular Neuroscience|November 3, 2018
A Purinergic P2 Receptor Family-Mediated Increase in Thrombospondin-1 Bolsters Synaptic Density and Epileptic Seizure Activity in the Amygdala-Kindling Rat ModelHongliu Sun, Luyu Ma, Yurong Zhang, et al.Frontiers in Immunology|August 15, 2022
A Study on the Radiosensitivity of Radiation-Induced Lung Injury at the Acute Phase Based on Single-Cell TranscriptomicsLuyu Ma, Yumeng Ye, Hao Lu, et al.Pageof 2