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Molecular Cancer Therapeutics|November 18, 2020
Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor GrowthShauni Lien Geeraerts, Kim Rosalie Kampen, Gianmarco Rinaldi, et al.Journal of Experimental & Clinical Cancer Research : CR|April 19, 2023
Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapyAli Talebi, Vincent de Laat, Xander Spotbeen, et al.Science (New York, N.Y.)|January 27, 2023
Mitochondria metabolism sets the species-specific tempo of neuronal developmentRyohei Iwata, Pierre Casimir, Emir Erkol, et al.Nature Communications|May 20, 2020
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancerArnaud Blomme, Catriona A Ford, Ernest Mui, et al.Cell Reports|December 29, 2021
Macrophages are metabolically heterogeneous within the tumor microenvironmentXenia Geeraerts, Juan Fernández-Garcia, Felix J Hartmann, et al.Nature Communications|August 5, 2022
Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancersTom Van Nyen, Mélanie Planque, Lilian van Wagensveld, et al.Cell Communication and Signaling : CCS|May 15, 2026
Periprostatic adipose tissue-derived adipokine profile in prostate cancer patients reveals two distinct molecular phenotypes linked to obesity-related comorbidities: multifaceted role of lipocalin-2Jesús M Pérez-Gómez, Antonio Prats-Escribano, Ignacio Gil-Duque, et al.Nature Communications|May 14, 2024
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolismTal Levy, Kai Voeltzke, Laura Hruby, et al.Cancer Research|March 10, 2021
Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver TumorigenesisLindsay A Broadfield, João André Gonçalves Duarte, Roberta Schmieder, et al.Nature|July 1, 2026
Steatosis shapes prognosis-defining liver metastasis heterogeneity in CRCYiming Peng-Winkler, Xiao-Zheng Liu, Sanne M L Verheul, et al.Pageof 4