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M A Naylor

Showing results (21-30 of 34) with videos related to

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Anti-Cancer Drug Design|April 3, 1998
5-substituted analogues of 3-hydroxymethyl-5-aziridinyl-1-methyl-2-[1H-indole-4,7-dione]prop-2-en- 1-ol (EO9, NSC 382459) and their regioisomers as hypoxia-selective agents: structure-cytotoxicity in vitroM Jaffar, M A Naylor, N Robertson, et al.
Biochemical Pharmacology|February 29, 2000
The relative importance of NADPH: cytochrome c (P450) reductase for determining the sensitivity of human tumour cells to the indolequinone EO9 and related analogues lacking functionality at the C-2 and C-3 positionsM P Saunders, M Jaffar, A V Patterson, et al.
Journal of Medicinal Chemistry|September 1, 1990
Synthesis and evaluation of novel electrophilic nitrofuran carboxamides and carboxylates as radiosensitizers and bioreductively activated cytotoxinsM A Naylor, M A Stephens, S Cole, et al.
Anti-Cancer Drugs|April 1, 1995
Fused pyrazine mono-N-oxides as bioreductive drugs. III. Characterization of RB 90740 in vitro and in vivoM A Naylor, G E Adams, A Haigh, et al.
Acta Crystallographica. Section C, Crystal Structure Communications|February 15, 2001
1-Methylindole-3-carboxaldehyde oxime derivativesR W Janes, B S Potter, M A Naylor, et al.
Journal of Medicinal Chemistry|October 9, 1999
Bioreductive activation of a series of indolequinones by human DT-diaphorase: structure-activity relationshipsR M Phillips, M A Naylor, M Jaffar, et al.
Journal of Medicinal Chemistry|July 1, 1991
Synthesis of a series of nitrothiophenes with basic or electrophilic substituents and evaluation as radiosensitizers and as bioreductively activated cytotoxinsM D Threadgill, P Webb, P O'Neill, et al.
Anti-Cancer Drug Design|July 1, 1991
Aziridinyl nitropyrroles and nitropyrazoles as hypoxia-selective cytotoxins and radiosensitizersM A Naylor, M A Stephens, I J Stratford, et al.
Journal of Medicinal Chemistry|July 18, 1997
2-Cyclopropylindoloquinones and their analogues as bioreductively activated antitumor agents: structure-activity in vitro and efficacy in vivoM A Naylor, M Jaffar, J Nolan, et al.
The British Journal of Cancer. Supplement|July 1, 1996
Chemical properties which control selectivity and efficacy of aromatic N-oxide bioreductive drugsP Wardman, K I Priyadarsini, M F Dennis, et al.
Pageof 4

Showing results (21-30 of 34) with videos related to

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Pageof 4
Anti-Cancer Drug Design|April 3, 1998
5-substituted analogues of 3-hydroxymethyl-5-aziridinyl-1-methyl-2-[1H-indole-4,7-dione]prop-2-en- 1-ol (EO9, NSC 382459) and their regioisomers as hypoxia-selective agents: structure-cytotoxicity in vitroM Jaffar, M A Naylor, N Robertson, et al.
Biochemical Pharmacology|February 29, 2000
The relative importance of NADPH: cytochrome c (P450) reductase for determining the sensitivity of human tumour cells to the indolequinone EO9 and related analogues lacking functionality at the C-2 and C-3 positionsM P Saunders, M Jaffar, A V Patterson, et al.
Journal of Medicinal Chemistry|September 1, 1990
Synthesis and evaluation of novel electrophilic nitrofuran carboxamides and carboxylates as radiosensitizers and bioreductively activated cytotoxinsM A Naylor, M A Stephens, S Cole, et al.
Anti-Cancer Drugs|April 1, 1995
Fused pyrazine mono-N-oxides as bioreductive drugs. III. Characterization of RB 90740 in vitro and in vivoM A Naylor, G E Adams, A Haigh, et al.
Acta Crystallographica. Section C, Crystal Structure Communications|February 15, 2001
1-Methylindole-3-carboxaldehyde oxime derivativesR W Janes, B S Potter, M A Naylor, et al.
Journal of Medicinal Chemistry|October 9, 1999
Bioreductive activation of a series of indolequinones by human DT-diaphorase: structure-activity relationshipsR M Phillips, M A Naylor, M Jaffar, et al.
Journal of Medicinal Chemistry|July 1, 1991
Synthesis of a series of nitrothiophenes with basic or electrophilic substituents and evaluation as radiosensitizers and as bioreductively activated cytotoxinsM D Threadgill, P Webb, P O'Neill, et al.
Anti-Cancer Drug Design|July 1, 1991
Aziridinyl nitropyrroles and nitropyrazoles as hypoxia-selective cytotoxins and radiosensitizersM A Naylor, M A Stephens, I J Stratford, et al.
Journal of Medicinal Chemistry|July 18, 1997
2-Cyclopropylindoloquinones and their analogues as bioreductively activated antitumor agents: structure-activity in vitro and efficacy in vivoM A Naylor, M Jaffar, J Nolan, et al.
The British Journal of Cancer. Supplement|July 1, 1996
Chemical properties which control selectivity and efficacy of aromatic N-oxide bioreductive drugsP Wardman, K I Priyadarsini, M F Dennis, et al.
Pageof 4