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Biological Psychiatry
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November 13, 2012
Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity
Jerri M Rook, Meredith J Noetzel, Wendy A Pouliot, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 5, 2018
Corrigendum to "Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides" [Bioorg. Med. Chem. Lett. 27(23) (2017) 5179-5184]
James C Tarr, Michael R Wood, Meredith J Noetzel, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 2, 2017
Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides
James C Tarr, Michael R Wood, Meredith J Noetzel, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2021
Discovery of VU6028418: A Highly Selective and Orally Bioavailable M<sub>4</sub> Muscarinic Acetylcholine Receptor Antagonist
Matthew Spock, Trever R Carter, Katrina A Bollinger, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
October 10, 2008
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Carrie K Jones, Ashley E Brady, Albert A Davis, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 17, 2015
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
María Luz Martín-Martín, José Manuel Bartolomé-Nebreda, Susana Conde-Ceide, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
November 13, 2009
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning
Jana K Shirey, Ashley E Brady, Paulianda J Jones, et al.
Molecular Cell
|
December 30, 2014
Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease
Madushi Raththagala, M Kathryn Brewer, Matthew W Parker, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
January 21, 2014
Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100
Nellie E Byun, Michael Grannan, Michael Bubser, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 13, 2016
Challenges in the development of an M<sub>4</sub> PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs
Michael R Wood, Meredith J Noetzel, Michael S Poslusney, et al.
Page
of 41
Search research articles
Search
Showing results (371-380 of 403) with videos related to
Sort By:
Page
of 41
Biological Psychiatry
|
November 13, 2012
Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity
Jerri M Rook, Meredith J Noetzel, Wendy A Pouliot, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 5, 2018
Corrigendum to "Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides" [Bioorg. Med. Chem. Lett. 27(23) (2017) 5179-5184]
James C Tarr, Michael R Wood, Meredith J Noetzel, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 2, 2017
Challenges in the development of an M<sub>4</sub> PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides
James C Tarr, Michael R Wood, Meredith J Noetzel, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2021
Discovery of VU6028418: A Highly Selective and Orally Bioavailable M<sub>4</sub> Muscarinic Acetylcholine Receptor Antagonist
Matthew Spock, Trever R Carter, Katrina A Bollinger, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
October 10, 2008
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Carrie K Jones, Ashley E Brady, Albert A Davis, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 17, 2015
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
María Luz Martín-Martín, José Manuel Bartolomé-Nebreda, Susana Conde-Ceide, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
November 13, 2009
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning
Jana K Shirey, Ashley E Brady, Paulianda J Jones, et al.
Molecular Cell
|
December 30, 2014
Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease
Madushi Raththagala, M Kathryn Brewer, Matthew W Parker, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
January 21, 2014
Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100
Nellie E Byun, Michael Grannan, Michael Bubser, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 13, 2016
Challenges in the development of an M<sub>4</sub> PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs
Michael R Wood, Meredith J Noetzel, Michael S Poslusney, et al.
Page
of 41