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Proceedings of the National Academy of Sciences of the United States of America|November 12, 1996
Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activitiesM Citron, T S Diehl, G Gordon, et al.Neurobiology of Disease|January 1, 1997
Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissueM B Podlisny, M Citron, P Amarante, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 12, 1999
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neuronsD M Hartley, D M Walsh, C P Ye, et al.The Biochemical Journal|October 1, 1995
Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin SJ S Munger, C Haass, C A Lemere, et al.Biochemistry|April 2, 1998
Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo redM B Podlisny, D M Walsh, P Amarante, et al.The Journal of Biological Chemistry|August 25, 2000
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretaseB D Bennett, P Denis, M Haniu, et al.The Journal of Biological Chemistry|August 28, 1999
Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediatesD M Walsh, D M Hartley, Y Kusumoto, et al.Nature Medicine|December 1, 1995
The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathwayC Haass, C A Lemere, A Capell, et al.Current Opinion in Neurobiology|February 19, 2000
Notch and presenilins in vertebrates and invertebrates: implications for neuronal development and degenerationD J SelkoeProceedings of the National Academy of Sciences of the United States of America|September 27, 2001
Presenilin, Notch, and the genesis and treatment of Alzheimer's diseaseD J SelkoePageof 77