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Biorxiv : the Preprint Server for Biology|September 30, 2024
Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinomaElizabeth R Woodruff, Courtney A Bailey, Francis To, et al.The Journal of Biological Chemistry|October 5, 2011
Mechanistic studies of substrate-assisted inhibition of ubiquitin-activating enzyme by adenosine sulfamate analoguesJesse J Chen, Christopher A Tsu, James M Gavin, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|November 20, 2015
De novo generation of adipocytes from circulating progenitor cells in mouse and human adipose tissueKathleen M Gavin, Jonathan A Gutman, Wendy M Kohrt, et al.Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA|July 24, 2015
The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension studyS Papapoulos, K Lippuner, C Roux, et al.Cancer Cell|March 24, 2012
Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924Michael A Milhollen, Michael P Thomas, Usha Narayanan, et al.Nature Immunology|June 9, 2016
Control of the innate immune response by the mevalonate pathwayMurali K Akula, Man Shi, Zhaozhao Jiang, et al.Science Translational Medicine|September 15, 2021
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical modelsEric S Lightcap, Pengfei Yu, Stephen Grossman, et al.Molecular Cell|February 5, 2010
Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situJames E Brownell, Michael D Sintchak, James M Gavin, et al.Nature|April 11, 2009
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancerTeresa A Soucy, Peter G Smith, Michael A Milhollen, et al.Pageof 11