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ACS Chemical Biology|February 21, 2022
The HPK1 Inhibitor A-745 Verifies the Potential of Modulating T Cell Kinase Signaling for ImmunotherapySven Malchow, Alla Korepanova, Sanjay C Panchal, et al.Scientific Reports|August 26, 2022
Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal siteEric R Goedken, Maria A Argiriadi, Justin D Dietrich, et al.Journal of Medicinal Chemistry|September 25, 2008
Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligandsRobert J Altenbach, Ronald M Adair, Brian M Bettencourt, et al.Scientific Reports|June 26, 2019
Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque PsoriasisViktor Todorović, Zhi Su, C Brent Putman, et al.Molecular Psychiatry|October 19, 2005
Variants in Apaf-1 segregating with major depression promote apoptosome functionJ Harlan, Y Chen, E Gubbins, et al.Journal of Medicinal Chemistry|March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In VivoJohn T Randolph, Matthew J O'Connor, Fei Han, et al.Journal of Medicinal Chemistry|June 5, 2025
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library ScreenYunsong Tong, Kenton A Baker, Alex M Chapman, et al.Journal of Medicinal Chemistry|November 3, 2018
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug DesignAdrian D Hobson, Russell A Judge, Ana L Aguirre, et al.Journal of Medicinal Chemistry|May 25, 2026
Discovery of Potent and Orally Bioavailable Novel Cluster of Differentiation 38 (CD38) Small Molecule InhibitorsReza Shiroodi, Timothy J Montavon, Brandon M Nelson, et al.Pageof 27