M J Robins - JoVE Visualize

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The Journal of Biological Chemistry|July 11, 1998

A novel mechanism-based inhibitor (6'-bromo-5', 6'-didehydro-6'-deoxy-6'-fluorohomoadenosine) that covalently modifies human placental S-adenosylhomocysteine hydrolaseC S Yuan, S F Wnuk, M J Robins, et al.

Biochemistry|April 7, 1987

2'-Deoxy-2'-halonucleotides as alternate substrates and mechanism-based inactivators of Lactobacillus leichmannii ribonucleotide reductaseG Harris, G W Ashley, M J Robins, et al.

Biochemical and Biophysical Research Communications|May 29, 1987

The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replicationJ Balzarini, M J Robins, R M Zou, et al.

Biochemistry|December 7, 2000

Mechanisms of inactivation of human S-adenosylhomocysteine hydrolase by 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosinesX Yang, D Yin, S F Wnuk, et al.

Journal of Medicinal Chemistry|April 2, 1993

Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolaseS Liu, S F Wnuk, C Yuan, et al.

Antimicrobial Agents and Chemotherapy|March 1, 1989

In vitro and in vivo comparison of the abilities of purine and pyrimidine 2',3'-dideoxynucleosides to inhibit duck hepadnavirusB Lee, W X Luo, S Suzuki, et al.

Biochemical and Biophysical Research Communications|November 15, 1988

Inhibition of duck hepatitis B virus replication by purine 2',3'-dideoxynucleosidesS Suzuki, B Lee, W Luo, et al.

Biochemistry|October 11, 1994

(E)-5',6'-didehydro-6'-deoxy-6'-fluorohomoadenosine: a substrate that measures the hydrolytic activity of S-adenosylhomocysteine hydrolaseC S Yuan, S F Wnuk, S Liu, et al.

Cancer Treatment Reports|February 1, 1982

Comparison of the effects on cultured L1210 leukemia cells of the ribosyl, 2'-deoxyribosyl, and xylosyl homologs of tubercidin and adenosine alone or in combination with 2'-deoxycoformycinC E Cass, M Selner, T H Tan, et al.

Archives of Biochemistry and Biophysics|July 1, 1997

The mechanism of inactivation of human placental S-adenosylhomocysteine hydrolase by (E)-4',5'-didehydro-5'-methoxyadenosine and adenosine 5'-carboxaldehyde oximeH Huang, C S Yuan, S F Wnuk, et al.

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The Journal of Biological Chemistry|July 11, 1998

A novel mechanism-based inhibitor (6'-bromo-5', 6'-didehydro-6'-deoxy-6'-fluorohomoadenosine) that covalently modifies human placental S-adenosylhomocysteine hydrolaseC S Yuan, S F Wnuk, M J Robins, et al.

Biochemistry|April 7, 1987

2'-Deoxy-2'-halonucleotides as alternate substrates and mechanism-based inactivators of Lactobacillus leichmannii ribonucleotide reductaseG Harris, G W Ashley, M J Robins, et al.

Biochemical and Biophysical Research Communications|May 29, 1987

The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replicationJ Balzarini, M J Robins, R M Zou, et al.

Biochemistry|December 7, 2000

Mechanisms of inactivation of human S-adenosylhomocysteine hydrolase by 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosinesX Yang, D Yin, S F Wnuk, et al.

Journal of Medicinal Chemistry|April 2, 1993

Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolaseS Liu, S F Wnuk, C Yuan, et al.

Antimicrobial Agents and Chemotherapy|March 1, 1989

In vitro and in vivo comparison of the abilities of purine and pyrimidine 2',3'-dideoxynucleosides to inhibit duck hepadnavirusB Lee, W X Luo, S Suzuki, et al.

Biochemical and Biophysical Research Communications|November 15, 1988

Inhibition of duck hepatitis B virus replication by purine 2',3'-dideoxynucleosidesS Suzuki, B Lee, W Luo, et al.

Biochemistry|October 11, 1994

(E)-5',6'-didehydro-6'-deoxy-6'-fluorohomoadenosine: a substrate that measures the hydrolytic activity of S-adenosylhomocysteine hydrolaseC S Yuan, S F Wnuk, S Liu, et al.

Cancer Treatment Reports|February 1, 1982

Comparison of the effects on cultured L1210 leukemia cells of the ribosyl, 2'-deoxyribosyl, and xylosyl homologs of tubercidin and adenosine alone or in combination with 2'-deoxycoformycinC E Cass, M Selner, T H Tan, et al.

Archives of Biochemistry and Biophysics|July 1, 1997

The mechanism of inactivation of human placental S-adenosylhomocysteine hydrolase by (E)-4',5'-didehydro-5'-methoxyadenosine and adenosine 5'-carboxaldehyde oximeH Huang, C S Yuan, S F Wnuk, et al.

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