M J Robins - JoVE Visualize

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The Journal of Biological Chemistry|March 6, 1999

Binding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligandC C Lawrence, G J Gerfen, V Samano, et al.

The Journal of Biological Chemistry|November 5, 1992

Nucleobase transporter-mediated permeation of 2',3'-dideoxyguanosine in human erythrocytes and human T-lymphoblastoid CCRF-CEM cellsW P Gati, A R Paterson, D L Tyrrell, et al.

Journal of Medicinal Chemistry|September 28, 1998

Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine)M J Robins, S F Wnuk, X Yang, et al.

Biochemistry|June 13, 1998

Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphateW A van der Donk, G Yu, L Pérez, et al.

Biochemistry|November 30, 1993

Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphateS Salowe, J M Bollinger, M Ator, et al.

Journal of Medicinal Chemistry|June 12, 1992

Nucleic acid related compounds. 74. Synthesis and biological activity of 2'(and 3')-deoxy-2'(and 3')-methylenenucleoside analogues that function as mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase and/or ribonucleotide reductaseM J Robins, V Samano, W Zhang, et al.

Journal of Medicinal Chemistry|June 1, 1991

2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductaseC H Baker, J Banzon, J M Bollinger, et al.

Journal of Medicinal Chemistry|July 31, 1998

Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosineS F Wnuk, Y Mao, C S Yuan, et al.

Biochemical Pharmacology|April 1, 1988

Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyribosideR Pauwels, M Baba, J Balzarini, et al.

Journal of Medicinal Chemistry|March 29, 2000

Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effectsS F Wnuk, C A Valdez, J Khan, et al.

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Showing results (41-50 of 52) with videos related to

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The Journal of Biological Chemistry|March 6, 1999

Binding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligandC C Lawrence, G J Gerfen, V Samano, et al.

The Journal of Biological Chemistry|November 5, 1992

Nucleobase transporter-mediated permeation of 2',3'-dideoxyguanosine in human erythrocytes and human T-lymphoblastoid CCRF-CEM cellsW P Gati, A R Paterson, D L Tyrrell, et al.

Journal of Medicinal Chemistry|September 28, 1998

Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine)M J Robins, S F Wnuk, X Yang, et al.

Biochemistry|June 13, 1998

Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphateW A van der Donk, G Yu, L Pérez, et al.

Biochemistry|November 30, 1993

Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphateS Salowe, J M Bollinger, M Ator, et al.

Journal of Medicinal Chemistry|June 12, 1992

Nucleic acid related compounds. 74. Synthesis and biological activity of 2'(and 3')-deoxy-2'(and 3')-methylenenucleoside analogues that function as mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase and/or ribonucleotide reductaseM J Robins, V Samano, W Zhang, et al.

Journal of Medicinal Chemistry|June 1, 1991

2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductaseC H Baker, J Banzon, J M Bollinger, et al.

Journal of Medicinal Chemistry|July 31, 1998

Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosineS F Wnuk, Y Mao, C S Yuan, et al.

Biochemical Pharmacology|April 1, 1988

Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyribosideR Pauwels, M Baba, J Balzarini, et al.

Journal of Medicinal Chemistry|March 29, 2000

Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effectsS F Wnuk, C A Valdez, J Khan, et al.

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