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Methods in Molecular Medicine|March 2, 2011
Isolation and culture of human hepatocytesM K Bayliss, P SkettCurrent Opinion in Drug Discovery & Development|August 4, 2009
High-throughput pharmacokinetics: cassette dosingM K Bayliss, L W FrickDrug Metabolism Reviews|April 25, 2000
A commentary on the use of hepatocytes in drug metabolism studies during drug discovery and developmentD M Cross, M K BaylissDrug Discovery Today|September 21, 2001
Combining high-throughput pharmacokinetic screens at the hits-to-leads stage of drug discoveryD J.M. Spalding, A J. Harker, M K. BaylissXenobiotica; the Fate of Foreign Compounds in Biological Systems|August 19, 2007
The metabolism of the 5HT3 antagonists, ondansetron, alosetron and GR87442 II: investigation into the in vitro methods used to predict the in vivo hepatic clearance of ondansetron, alosetron and GR87442 in the rat, dog and humanG I Somers, M K Bayliss, J B HoustonBritish Journal of Clinical Pharmacology|June 26, 1999
Microsomal prediction of in vivo clearance of CYP2C9 substrates in humansD J Carlile, N Hakooz, M K Bayliss, et al.Rapid Communications in Mass Spectrometry : RCM|November 21, 2000
Parallel ultra-high flow rate liquid chromatography with mass spectrometric detection using a multiplex electrospray source for direct, sensitive determination of pharmaceuticals in plasma at extremely high throughputM K Bayliss, D Little, D N Mallett, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 1, 1994
7-Ethoxycoumarin O-deethylase kinetics in isolated rat, dog and human hepatocyte suspensionsM K Bayliss, J A Bell, K Wilson, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 19, 2007
The metabolism of the 5HT3 antagonists ondansetron, alosetron and GR87442 I: a comparison of in vitro and in vivo metabolism and in vitro enzyme kinetics in rat, dog and human hepatocytes, microsomes and recombinant human enzymesG I Somers, A J Harris, M K Bayliss, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|April 29, 1999
Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and manM K Bayliss, J A Bell, W N Jenner, et al.Pageof 2