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Cytokines and Molecular Therapy|March 1, 1995
Transfer of the MDR1 (multidrug resistance) gene: protection of hematopoietic cells from cytotoxic chemotherapy, and selection of transduced cells in vivoT Licht, M M Gottesman, I PastanProceedings of the National Academy of Sciences of the United States of America|May 1, 1987
Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastineK Ueda, C Cardarelli, M M Gottesman, et al.Human Gene Therapy|March 21, 2000
Chemoprotection of hematopoietic cells by a mutant P-glycoprotein resistant to a potent chemosensitizer of multidrug-resistant cancersP Hafkemeyer, T Licht, I Pastan, et al.Annals of Hematology|April 1, 1996
The multidrug-resistance gene in gene therapy of cancer and hematopoietic disordersT Licht, I Pastan, M M Gottesman, et al.Blood|July 1, 1995
Efficient expression of functional human MDR1 gene in murine bone marrow after retroviral transduction of purified hematopoietic stem cellsT Licht, I Aksentijevich, M M Gottesman, et al.Stem Cells (Dayton, Ohio)|January 1, 1997
In vivo drug-selectable genes: a new concept in gene therapyT Licht, F Herrmann, M M Gottesman, et al.Molecular Pharmacology|April 1, 1994
Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substratesW D Stein, C Cardarelli, I Pastan, et al.Human Gene Therapy|November 10, 1996
Complete restoration of glucocerebrosidase deficiency in Gaucher fibroblasts using a bicistronic MDR retrovirus and a new selection strategyJ M Aran, T Licht, M M Gottesman, et al.Journal of Cellular Physiology|March 4, 2000
Decreased accumulation of [14C]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptakeD W Shen, S Goldenberg, I Pastan, et al.Gene Therapy|March 1, 2000
Drug selection of MDR1-transduced hematopoietic cells ex vivo increases transgene expression and chemoresistance in reconstituted bone marrow in miceT Licht, S K Goldenberg, W D Vieira, et al.Pageof 99