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M Manoharan

Showing results (91-100 of 103) with videos related to

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Biorxiv : the Preprint Server for Biology|April 16, 2025
Pregnancy-Dependent Cardioprotection via GPER Activation in Dahl Salt-Sensitive RatsAllan K N Alencar, Kenneth F Swan, Mistina M Manoharan, et al.
Annals of the New York Academy of Sciences|October 28, 1992
Chemical modifications to improve uptake and bioavailability of antisense oligonucleotidesM Manoharan, L K Johnson, D P McGee, et al.
Nucleic Acids Research|July 25, 2000
Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugationM K Bijsterbosch, E T Rump, R L De Vrueh, et al.
Biopolymers|March 4, 2000
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolutionM Egli, V Tereshko, M Teplova, et al.
Nucleic Acids Research|August 15, 1997
In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cellsM K Bijsterbosch, M Manoharan, E T Rump, et al.
The Journal of Organic Chemistry|March 5, 2016
Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified OligonucleotidesAlexander V Kel'in, Ivan Zlatev, Joel Harp, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 18, 2007
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficitsM DiFiglia, M Sena-Esteves, K Chase, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 1, 1996
Pharmacokinetic properties of several novel oligonucleotide analogs in miceS T Crooke, M J Graham, J E Zuckerman, et al.
Nucleic Acids Research|July 16, 2021
Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivoHartmut Jahns, Nate Taneja, Jennifer L S Willoughby, et al.
ACS Chemical Biology|March 3, 2015
siRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytesShigeo Matsuda, Kristofer Keiser, Jayaprakash K Nair, et al.
Pageof 11

Showing results (91-100 of 103) with videos related to

Sort By:
Pageof 11
Biorxiv : the Preprint Server for Biology|April 16, 2025
Pregnancy-Dependent Cardioprotection via GPER Activation in Dahl Salt-Sensitive RatsAllan K N Alencar, Kenneth F Swan, Mistina M Manoharan, et al.
Annals of the New York Academy of Sciences|October 28, 1992
Chemical modifications to improve uptake and bioavailability of antisense oligonucleotidesM Manoharan, L K Johnson, D P McGee, et al.
Nucleic Acids Research|July 25, 2000
Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugationM K Bijsterbosch, E T Rump, R L De Vrueh, et al.
Biopolymers|March 4, 2000
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolutionM Egli, V Tereshko, M Teplova, et al.
Nucleic Acids Research|August 15, 1997
In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cellsM K Bijsterbosch, M Manoharan, E T Rump, et al.
The Journal of Organic Chemistry|March 5, 2016
Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified OligonucleotidesAlexander V Kel'in, Ivan Zlatev, Joel Harp, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 18, 2007
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficitsM DiFiglia, M Sena-Esteves, K Chase, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 1, 1996
Pharmacokinetic properties of several novel oligonucleotide analogs in miceS T Crooke, M J Graham, J E Zuckerman, et al.
Nucleic Acids Research|July 16, 2021
Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivoHartmut Jahns, Nate Taneja, Jennifer L S Willoughby, et al.
ACS Chemical Biology|March 3, 2015
siRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytesShigeo Matsuda, Kristofer Keiser, Jayaprakash K Nair, et al.
Pageof 11