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Molecular Cell|February 24, 2015
Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell deathGabriel Ichim, Jonathan Lopez, Shafiq U Ahmed, et al.Biorxiv : the Preprint Server for Biology|August 7, 2023
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibitionGregory C Howard, Jing Wang, Kristie Lindsey Rose, et al.Cell Reports|August 25, 2015
Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle ArrestDina Dikovskaya, John J Cole, Susan M Mason, et al.Journal of Medicinal Chemistry|February 28, 2015
The discovery of Polo-like kinase 4 inhibitors: identification of (1R,2S).2-(3-((E).4-(((cis).2,6-dimethylmorpholino)methyl)styryl). 1H.indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one (CFI-400945) as a potent, orally active antitumor agentPeter B Sampson, Yong Liu, Bryan Forrest, et al.Cancers|July 13, 2024
Defining and Addressing Research Priorities in Cancer Cachexia through Transdisciplinary CollaborationMargaret A Park, Christopher J Whelan, Sabeen Ahmed, et al.Journal of Medicinal Chemistry|May 29, 2014
The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agentsPeter B Sampson, Yong Liu, Narendra Kumar Patel, et al.Cancer Research|May 5, 2018
<i>SETD2</i> Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell CarcinomaYun-Chen Chiang, In-Young Park, Esteban A Terzo, et al.Bioorganic & Medicinal Chemistry Letters|May 16, 2006
Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitorsNigel S Watson, David Brown, Matthew Campbell, et al.Cancers|March 28, 2025
Correction: Park et al. Defining and Addressing Research Priorities in Cancer Cachexia through Transdisciplinary Collaboration. <i>Cancers</i> 2024, <i>16</i>, 2364Margaret A Park, Christopher J Whelan, Sabeen Ahmed, et al.Bioorganic & Medicinal Chemistry Letters|December 7, 2007
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifsRobert J Young, Alan D Borthwick, David Brown, et al.Pageof 139