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ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of Pyrazolo[1,5-a]pyrimidine TTK Inhibitors: CFI-402257 is a Potent, Selective, Bioavailable Anticancer AgentYong Liu, Radoslaw Laufer, Narendra Kumar Patel, et al.Bioorganic & Medicinal Chemistry Letters|November 23, 2007
The discovery of GSK221149A: a potent and selective oxytocin antagonistJohn Liddle, Michael J Allen, Alan D Borthwick, et al.Bioorganic & Medicinal Chemistry Letters|September 20, 2006
Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifsRobert J Young, Matthew Campbell, Alan D Borthwick, et al.Antimicrobial Agents and Chemotherapy|November 25, 2004
Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimenSimon J F Macdonald, Keith G Watson, Rachel Cameron, et al.Bioorganic & Medicinal Chemistry Letters|December 7, 2007
Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifsRobert J Young, Alan D Borthwick, David Brown, et al.Nature Communications|March 10, 2022
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locusDavid Stacey, Lingyan Chen, Paulina J Stanczyk, et al.Cancer Cell|January 27, 2015
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progressionIsaac S Harris, Aislinn E Treloar, Satoshi Inoue, et al.Bioorganic & Medicinal Chemistry|July 22, 2014
Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamidesRadoslaw Laufer, Grace Ng, Yong Liu, et al.Journal of Medicinal Chemistry|March 13, 2015
The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as Anticancer AgentsYong Liu, Yunhui Lang, Narendra Kumar Patel, et al.Biorxiv : the Preprint Server for Biology|January 20, 2025
Impaired oxidative phosphorylation drives primary tumor escape and metastasisEmily N Arner, Erin Q Jennings, Daniel R Crooks, et al.Pageof 139