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Cell Reports|June 26, 2025
A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiencyBerenice Cabrera-Martinez, Josselyn E Garcia-Perez, Ryan M Baxter, et al.Stem Cell Reports|November 4, 2022
Maternal Western-style diet remodels the transcriptional landscape of fetal hematopoietic stem and progenitor cells in rhesus macaquesSuhas Sureshchandra, Chi N Chan, Jacob J Robino, et al.Cell Stem Cell|October 16, 2024
A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune miceTaylor S Mills, Bailee Kain, Matt A Burchill, et al.Cell Reports|April 7, 2021
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunityGiulio Cavalli, Isak W Tengesdal, Mark Gresnigt, et al.Blood|July 18, 2019
TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of agingPavel Davizon-Castillo, Brandon McMahon, Sonia Aguila, et al.Haematologica|May 19, 2019
Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritisGiovanny Hernandez, Taylor S Mills, Jennifer L Rabe, et al.Nature Communications|April 16, 2025
Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesisKira A Young, Mohsen Hosseini, Jayna J Mistry, et al.The Journal of Experimental Medicine|April 15, 2021
PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stressJames S Chavez, Jennifer L Rabe, Dirk Loeffler, et al.Bioorganic & Medicinal Chemistry Letters|November 19, 2009
2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding modeMaria A Argiriadi, Anna M Ericsson, Christopher M Harris, et al.Proceedings of the National Academy of Sciences of the United States of America|March 2, 2021
Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansionIsak W Tengesdal, Dinoop R Menon, Douglas G Osborne, et al.Pageof 10