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ACS Chemical Neuroscience
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August 8, 2018
Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M<sub>1</sub> Positive Allosteric Modulators
Julie L Engers, Aaron M Bender, Jacob J Kalbfleisch, et al.
Journal of Pediatric Surgery
|
August 15, 2025
Meconium-Related Obstruction: Contemporary Experience in a Multi-Institutional Consortium
Jordan M Rook, Jamie E Anderson, Katelin P Kramer, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
October 29, 2015
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice
Tristano Pancani, Daniel J Foster, Mark S Moehle, et al.
JACC. Basic to Translational Science
|
December 14, 2023
Development of a Peripherally Restricted 5-HT<sub>2B</sub> Partial Agonist for Treatment of Pulmonary Arterial Hypertension
Michael S Valentine, Aaron M Bender, Sheila Shay, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
VU6010608, a Novel mGlu<sub>7</sub> NAM from a Series of <i>N</i>-(2-(1<i>H</i>-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides
Carson W Reed, Kevin M McGowan, Paul K Spearing, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
June 26, 2015
Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model
A Ghoshal, J M Rook, J W Dickerson, et al.
Journal of Medicinal Chemistry
|
September 21, 2013
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)
Mark Turlington, Meredith J Noetzel, Aspen Chun, et al.
ACS Chemical Neuroscience
|
September 24, 2024
Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)
Julie L Engers, Logan A Baker, Sichen Chang, et al.
ACS Chemical Neuroscience
|
April 28, 2018
A Novel M<sub>1</sub> PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity
Jerri M Rook, Jeanette L Bertron, Hyekyung P Cho, et al.
ACS Chemical Neuroscience
|
December 22, 2016
Diverse Effects on M<sub>1</sub> Signaling and Adverse Effect Liability within a Series of M<sub>1</sub> Ago-PAMs
Jerri M Rook, Masahito Abe, Hyekyung P Cho, et al.
Page
of 11
Search research articles
Search
Showing results (81-90 of 110) with videos related to
Sort By:
Page
of 11
ACS Chemical Neuroscience
|
August 8, 2018
Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M<sub>1</sub> Positive Allosteric Modulators
Julie L Engers, Aaron M Bender, Jacob J Kalbfleisch, et al.
Journal of Pediatric Surgery
|
August 15, 2025
Meconium-Related Obstruction: Contemporary Experience in a Multi-Institutional Consortium
Jordan M Rook, Jamie E Anderson, Katelin P Kramer, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
October 29, 2015
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice
Tristano Pancani, Daniel J Foster, Mark S Moehle, et al.
JACC. Basic to Translational Science
|
December 14, 2023
Development of a Peripherally Restricted 5-HT<sub>2B</sub> Partial Agonist for Treatment of Pulmonary Arterial Hypertension
Michael S Valentine, Aaron M Bender, Sheila Shay, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
VU6010608, a Novel mGlu<sub>7</sub> NAM from a Series of <i>N</i>-(2-(1<i>H</i>-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides
Carson W Reed, Kevin M McGowan, Paul K Spearing, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
June 26, 2015
Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model
A Ghoshal, J M Rook, J W Dickerson, et al.
Journal of Medicinal Chemistry
|
September 21, 2013
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)
Mark Turlington, Meredith J Noetzel, Aspen Chun, et al.
ACS Chemical Neuroscience
|
September 24, 2024
Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)
Julie L Engers, Logan A Baker, Sichen Chang, et al.
ACS Chemical Neuroscience
|
April 28, 2018
A Novel M<sub>1</sub> PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity
Jerri M Rook, Jeanette L Bertron, Hyekyung P Cho, et al.
ACS Chemical Neuroscience
|
December 22, 2016
Diverse Effects on M<sub>1</sub> Signaling and Adverse Effect Liability within a Series of M<sub>1</sub> Ago-PAMs
Jerri M Rook, Masahito Abe, Hyekyung P Cho, et al.
Page
of 11