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Molecular Endocrinology (Baltimore, Md.)|July 19, 2013
Minireview: Signal bias, allosterism, and polymorphic variation at the GLP-1R: implications for drug discoveryCassandra Koole, Emilia E Savage, Arthur Christopoulos, et al.
Endocrinology|February 2, 2013
Impact of clinically relevant mutations on the pharmacoregulation and signaling bias of the calcium-sensing receptor by positive and negative allosteric modulatorsKatie Leach, Adriel Wen, Anna E Cook, et al.
Bioorganic & Medicinal Chemistry Letters|May 27, 2011
The synthesis and biological evaluation of 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophenes as allosteric modulators of the A1 adenosine receptorLuigi Aurelio, Arthur Christopoulos, Bernard L Flynn, et al.
Endocrinology|July 17, 2012
Identification of molecular phenotypes and biased signaling induced by naturally occurring mutations of the human calcium-sensing receptorKatie Leach, Adriel Wen, Anna E Davey, et al.
ACS Pharmacology & Translational Science|March 29, 2020
Rules of Engagement: GPCRs and G ProteinsAlisa Glukhova, Christopher J Draper-Joyce, Roger K Sunahara, et al.
The Journal of Biological Chemistry|March 12, 2017
Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)Cassandra Koole, Christopher A Reynolds, Juan C Mobarec, et al.
Biochemical and Biophysical Research Communications|January 7, 2000
Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene productE T Zumpe, N Tilakaratne, N J Fraser, et al.
Biochemical Pharmacology|September 25, 2008
Pharmacology of 5HT(2C) receptor-mediated ERK1/2 phosphorylation: agonist-specific activation pathways and the impact of RNA editingTim D Werry, Gregory D Stewart, Michael F Crouch, et al.
Clinical Genetics|April 1, 1997
The cholesteryl ester transfer protein (CETP) locus as a candidate gene in abdominal aortic aneurysmD Ramsbottom, A O'Neill, D M Sexton, et al.
Nature Communications|July 16, 2021
Routine sub-2.5 Å cryo-EM structure determination of GPCRsRadostin Danev, Matthew Belousoff, Yi-Lynn Liang, et al.
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