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Translational Oncology|February 19, 2022
Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of gliomaMari Kogiso, Lin Qi, Yuchen Du, et al.Journal of the American Chemical Society|August 31, 2021
Observation of an Intermediate to H2 Binding in a Metal-Organic FrameworkBrandon R Barnett, Hayden A Evans, Gregory M Su, et al.ACS Medicinal Chemistry Letters|February 20, 2020
Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of GliomaZenon Konteatis, Erin Artin, Brandon Nicolay, et al.Oncotarget|November 21, 2017
Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytomaMari Kogiso, Lin Qi, Holly Lindsay, et al.Science (New York, N.Y.)|April 6, 2013
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cellsDan Rohle, Janeta Popovici-Muller, Nicolaos Palaskas, et al.Science (New York, N.Y.)|April 6, 2013
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiationFang Wang, Jeremy Travins, Byron DeLaBarre, et al.Chemistry & Biology|September 25, 2012
Small molecule activation of PKM2 in cancer cells induces serine auxotrophyCharles Kung, Jeff Hixon, Sung Choe, et al.Gastroenterology|July 31, 2013
A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progressionWei-Yu Wang, Chung-Chi Hsu, Ting-Yun Wang, et al.Pediatric Blood & Cancer|June 14, 2021
Multi-institutional analysis of treatment modalities in basal ganglia and thalamic germinomaRichard T Graham, Mohammad H Abu-Arja, Joseph R Stanek, et al.ACS Medicinal Chemistry Letters|April 20, 2018
Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant CancersJaneta Popovici-Muller, René M Lemieux, Erin Artin, et al.Pageof 51