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The Journal of Pharmacology and Experimental Therapeutics|August 1, 1994
A new endothelin receptor antagonist, TAK-044, shows long-lasting inhibition of both ETA- and ETB-mediated blood pressure responses in ratsS Ikeda, Y Awane, K Kusumoto, et al.
Journal of Medicinal Chemistry|December 10, 1993
Endothelin-1 analogues substituted at both position 18 and 19: highly potent endothelin antagonists with no selectivity for either receptor subtype ETA or ETBT Kikuchi, K Kubo, T Ohtaki, et al.
European Journal of Pharmacology|May 1, 1997
Antagonist activity of [Thr18,gamma-methylleucine19]endothelin-1 in human endothelin receptorsY Masuda, T Sugo, T Kikuchi, et al.
Life Sciences|January 1, 1994
Effects of a new endothelin antagonist, TAK-044, on post-ischemic acute renal failure in ratsK Kusumoto, K Kubo, H Kandori, et al.
Regulatory Peptides|June 1, 1981
Presence of dynorphin-like immunoreactivity in rat pituitary gland and hypothalamusK Nakao, T Yoshimasa, S Oki, et al.
Journal of Cardiovascular Pharmacology|January 1, 1993
Pharmacologic profile of endothelinA/B antagonist, [Thr18, gamma methyl Leu19]endothelin-1N Shimamoto, K Kubo, T Watanabe, et al.
Growth Factors (Chur, Switzerland)|January 1, 1992
Identification of bone morphogenetic protein-2 in early Xenopus laevis embryosN Ueno, A Shoda, K Takebayashi, et al.
British Journal of Pharmacology|March 1, 1995
Pharmacology of a non-selective ETA and ETB receptor antagonist, TAK-044 and the inhibition of myocardial infarct size in ratsT Watanabe, Y Awane, S Ikeda, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 1, 1996
Receptor binding and antagonist properties of a novel endothelin receptor antagonist, TAK-044 [cyclo[D-alpha-aspartyl-3-[(4-phenylpiperazin-1-yl) carbonyl]-L-alanyl-L-alpha-aspartyl-D-2-(2-thienyl) glycyl-L-leucyl-D-tryptophyl]disodium salt], in human endothelinA and endothelinB receptorsY Masuda, T Sugo, T Kikuchi, et al.
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