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Cell Reports. Medicine|June 10, 2022
RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cellsZhengkui Zhang, Xiangjun Kong, Maarten A Ligtenberg, et al.Cancer Research|February 3, 2021
Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint BlockadeJulia Boshuizen, Nora Pencheva, Oscar Krijgsman, et al.Nature Communications|April 9, 2022
Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signalingGeorgi Apriamashvili, David W Vredevoogd, Oscar Krijgsman, et al.Nature Communications|August 10, 2020
Reversal of pre-existing NGFR-driven tumor and immune therapy resistanceJulia Boshuizen, David W Vredevoogd, Oscar Krijgsman, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|July 7, 2021
Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4Oscar Krijgsman, Kristel Kemper, Julia Boshuizen, et al.Cell|July 16, 2019
Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity ThresholdDavid W Vredevoogd, Thomas Kuilman, Maarten A Ligtenberg, et al.Nature Medicine|January 16, 2018
Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitorsJulia Boshuizen, Louise A Koopman, Oscar Krijgsman, et al.Journal for Immunotherapy of Cancer|November 7, 2024
TMED inhibition suppresses cell surface PD-1 expression and overcomes T cell dysfunctionDavid W Vredevoogd, Georgi Apriamashvili, Pierre L Levy, et al.Cancer Cell|March 15, 2024
Multimodal stimulation screens reveal unique and shared genes limiting T cell fitnessChun-Pu Lin, Pierre L Levy, Astrid Alflen, et al.Pageof 2