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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 1, 2016
The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic LeukemiaThomas Vercruysse, Jolien De Bie, Jasper E Neggers, et al.Science Translational Medicine|June 29, 2018
Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomasNatalia Saenz-Ponce, Rachael Pillay, Lilia Merida de Long, et al.Cell Reports|December 5, 2025
Sec61 translocon inhibitor flavitransin blocks selectively dengue virus polyprotein insertion in the ER with pan-orthoflavivirus antiviral potencyMarijke Verhaegen, Marianne Croonenborghs, Nidhi Sorout, et al.The Journal of Experimental Medicine|January 28, 2021
Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesisAdeline Rosu, Najla El Hachem, Francesca Rapino, et al.EMBO Reports|September 24, 2019
STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoesAlexandre Pj Martin, Maarten Jacquemyn, Joanna Lipecka, et al.Cell Death Discovery|March 23, 2026
ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbancesLisa Ehlers, Marjon Wouters, Bethany Pillay, et al.Nature Chemical Biology|November 25, 2025
SINE compounds activate exportin 1 degradation through an allosteric mechanismCasey E Wing, Ho Yee Joyce Fung, Bert Kwanten, et al.Science Advances|July 19, 2024
Targeting conserved TIM3+VISTA+ tumor-associated macrophages overcomes resistance to cancer immunotherapyIsaure Vanmeerbeek, Stefan Naulaerts, Jenny Sprooten, et al.Nature Communications|October 2, 2024
Intrinsic temperature increase drives lipid metabolism towards ferroptosis evasion and chemotherapy resistance in pancreatic cancerVincent de Laat, Halit Topal, Xander Spotbeen, et al.Nature Genetics|March 9, 2021
Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2Jim Baggen, Leentje Persoons, Els Vanstreels, et al.Pageof 3