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The Journal of Biological Chemistry|December 10, 2016
Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1Jude T Chenge, Le Van Duyet, Shalini Swami, et al.Biorxiv : the Preprint Server for Biology|January 13, 2025
Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolismMadeline E Kavanagh, Kirsty J McLean, Sophie H Gilbert, et al.European Journal of Medicinal Chemistry|January 22, 2022
A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen)Martyn Frederickson, Irwin R Selvam, Dimitrios Evangelopoulos, et al.Journal of Medicinal Chemistry|July 14, 2025
Fragment-Based Development of Small Molecule Inhibitors Targeting Mycobacterium tuberculosis Cholesterol MetabolismMadeline E Kavanagh, Kirsty J McLean, Sophie H Gilbert, et al.Nature Chemical Biology|September 13, 2022
Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteineMadeline E Kavanagh, Benjamin D Horning, Roli Khattri, et al.Nature Communications|July 21, 2024
Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repressionGloria Asantewaa, Emily T Tuttle, Nathan P Ward, et al.Biorxiv : the Preprint Server for Biology|February 17, 2023
Glutathione supports lipid abundance in vivoGloria Asantewaa, Emily T Tuttle, Nathan P Ward, et al.Nature Chemistry|December 14, 2021
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitorsJürgen Brem, Tharindi Panduwawala, Jon Ulf Hansen, et al.Pageof 2