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Clinical Pharmacology in Drug Development|October 16, 2020
Multiple-Dose Pharmacokinetics, Safety, and Tolerability of Aprocitentan, a Dual Endothelin Receptor Antagonist, in Healthy Japanese and Caucasian SubjectsMagda S C Fontes, Jasper Dingemanse, Patricia N SidhartaScientific Reports|November 9, 2022
Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairmentMagda S C Fontes, Jasper Dingemanse, Atef Halabi, et al.Biochimica Et Biophysica Acta|August 16, 2011
Functional consequences of abnormal Cx43 expression in the heartMagda S C Fontes, Toon A B van Veen, Jacques M T de Bakker, et al.Plos One|February 6, 2014
Changes in Cx43 and NaV1.5 expression precede the occurrence of substantial fibrosis in calcineurin-induced murine cardiac hypertrophyMagda S C Fontes, Antonia J A Raaijmakers, Tessa van Doorn, et al.Journal of Molecular and Cellular Cardiology|September 28, 2015
CTGF knockout does not affect cardiac hypertrophy and fibrosis formation upon chronic pressure overloadMagda S C Fontes, Elise L Kessler, Leonie van Stuijvenberg, et al.Scientific Reports|August 25, 2017
Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure OverloadJiong-Wei Wang, Magda S C Fontes, Xiaoyuan Wang, et al.International Journal of Molecular Sciences|November 13, 2021
Ventricular TLR4 Levels Abrogate TLR2-Mediated Adverse Cardiac Remodeling upon Pressure Overload in MiceElise L Kessler, Jiong-Wei Wang, Bart Kok, et al.Cardiorenal Medicine|July 22, 2015
Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal DiseaseMagda S C Fontes, Diana A Papazova, Arianne van Koppen, et al.Cardiovascular Research|July 1, 2016
Calmodulin/CaMKII inhibition improves intercellular communication and impulse propagation in the heart and is antiarrhythmic under conditions when fibrosis is absentHiroki Takanari, Vincent J A Bourgonje, Magda S C Fontes, et al.Pageof 1