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Cell Death & Disease|December 20, 2022
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivoMagdalena Bachmann, Andrea Rossa, Tatiana Varanita, et al.Cell Reports|August 22, 2019
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress InductionRoberto Costa, Roberta Peruzzo, Magdalena Bachmann, et al.Journal of Experimental & Clinical Cancer Research : CR|February 17, 2022
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL modelFilippo Severin, Andrea Urbani, Tatiana Varanita, et al.Pharmacological Research|February 21, 2026
Tumor-specific targeting of a mitochondrial Kv1.3 channel inhibitor through conjugation to gastrin/cholecystokinin B receptor ligand strongly reduces pancreatic ductal adenocarcinoma in orthotopic modelsSofia Parrasia, Carlotta Paoli, Tatiana Varanita, et al.Science Advances|September 4, 2024
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathwayElena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, et al.Pageof 3