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Molecular Pharmacology|October 19, 2019
Comparative Docking to Distinct G Protein-Coupled Receptor Conformations Exclusively Yields Ligands with Agonist EfficacyMagdalena M Scharf, Moritz Bünemann, Jillian G Baker, et al.ACS Pharmacology & Translational Science|January 19, 2023
Viewpoint on the Second Transatlantic GPCR Symposium for Early Career InvestigatorsJohn Janetzko, Cory P Johnson, Paula Morales, et al.Chemmedchem|April 18, 2020
A Focus on Unusual ECL2 Interactions Yields β2 -Adrenergic Receptor Antagonists with Unprecedented ScaffoldsMagdalena M Scharf, Mirjam Zimmermann, Florian Wilhelm, et al.Trends in Pharmacological Sciences|April 9, 2024
Frizzleds act as dynamic pharmacological entitiesGunnar Schulte, Magdalena M Scharf, Julien Bous, et al.Molecules (Basel, Switzerland)|February 3, 2021
Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target ScreeningDenis Schmidt, Magdalena M Scharf, Dominique Sydow, et al.Nature Communications|August 28, 2024
Structural basis of frizzled 7 activation and allosteric regulationJulien Bous, Julia Kinsolving, Lukas Grätz, et al.Nature Communications|December 14, 2025
In silico docking yields small molecule negative allosteric modulators targeting the core of Frizzled 7Magdalena M Scharf, Julia Kinsolving, Lukas Grätz, et al.Nature Communications|July 29, 2023
Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformationsLukas Grätz, Maria Kowalski-Jahn, Magdalena M Scharf, et al.European Journal of Medicinal Chemistry|August 14, 2025
Water molecules in the cannabinoid receptor 2 binding site crucially impact the discovery of novel ligandsMagdalena M Scharf, Morgan Scott-Dennis, Leire Borrega-Roman, et al.British Journal of Pharmacology|February 10, 2024
The dark sides of the GPCR tree - research progress on understudied GPCRsMagdalena M Scharf, Laura J Humphrys, Sandra Berndt, et al.Pageof 2