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Bioorganic & Medicinal Chemistry|July 23, 2018
Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockersHuy Du Nguyen, Takuya Okada, Shun Kitamura, et al.Journal of Pharmacological Sciences|February 18, 2022
Development of hepatic impairment aggravates chemotherapy-induced peripheral neuropathy following oxaliplatin treatment: Evidence from clinical and preclinical studiesTomoyoshi Miyamoto, Risa Domoto, Fumiko Sekiguchi, et al.European Journal of Pharmacology|September 19, 2020
Essential role of Cav3.2 T-type calcium channels in butyrate-induced colonic pain and nociceptor hypersensitivity in miceMaho Tsubota, Kazuki Matsui, Maki Nakano, et al.European Journal of Pharmacology|April 24, 2025
HMGB1 derived from macrophages and enteric glial cells contributes to the butyrate-induced colonic hypersensitivity in miceMaho Tsubota, Kana Sasaki, Eunkyung Shin, et al.Journal of Pharmacological Sciences|September 8, 2019
Genetic deletion of Cav3.2 T-type calcium channels abolishes H2S-dependent somatic and visceral pain signaling in C57BL/6 miceKazuki Matsui, Maho Tsubota, Saaya Fukushi, et al.European Journal of Medicinal Chemistry|September 8, 2022
Discovery of pimozide derivatives as novel T-type calcium channel inhibitors with little binding affinity to dopamine D2 receptors for treatment of somatic and visceral painYoshihito Kasanami, Chihiro Ishikawa, Takahiro Kino, et al.Journal of Neuroinflammation|November 1, 2019
Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of anticoagulantsMaho Tsubota, Ryotaro Fukuda, Yusuke Hayashi, et al.Redox Biology|December 23, 2022
A hydrolysate of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) suppresses Cav3.2-dependent pain by sequestering exogenous and endogenous sulfideFumiko Sekiguchi, Nene Koike, Yasuhiro Shimada, et al.Scientific Reports|January 10, 2024
Clinical and preclinical evidence that angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prevent diabetic peripheral neuropathyShiori Iwane, Wataru Nemoto, Tomoyoshi Miyamoto, et al.Cells|July 26, 2020
Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream H2S/Cav3.2 Signaling in MiceShiori Hiramoto, Maho Tsubota, Kaoru Yamaguchi, et al.Pageof 7