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Journal of Pharmaceutical Sciences|November 19, 2018
Evaluation of Cytochrome P450 Selectivity for Hydralazine as an Aldehyde Oxidase Inhibitor for Reaction PhenotypingXin Yang, Nathaniel Johnson, Li Di
Journal of Medicinal Chemistry|October 19, 2012
Demystifying brain penetration in central nervous system drug discovery. MiniperspectiveLi Di, Haojing Rong, Bo Feng
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 25, 2015
Novel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay MethodXin Yang, Karen Atkinson, Li Di
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|September 14, 2020
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytesChristopher Keefer, George Chang, Anthony Carlo, et al.
Drug Discovery Today|December 6, 2011
Bridging solubility between drug discovery and developmentLi Di, Paul V Fish, Takashi Mano
Pharmaceutical Research|March 8, 2022
In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical SpeciesDavid A Tess, Sangwoo Ryu, Li Di
Biopharmaceutics & Drug Disposition|February 24, 2021
Effects of low temperature on blood-to-plasma ratio measurementJonathan J Novak, Woodrow Burchett, Li Di
The AAPS Journal|March 20, 2019
Theoretical Considerations for Direct Translation of Unbound Liver-to-Plasma Partition Coefficient from In Vitro to In VivoZhenhong Li, Li Di, Tristan S Maurer
Pharmaceutical Research|May 25, 2023
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption KineticsKazuko Sagawa, Jian Lin, Rohit Jaini, et al.
Cell and Tissue Research|August 7, 2012
Harlequin ichthyosis: ABCA12 mutations underlie defective lipid transport, reduced protease regulation and skin-barrier dysfunctionClaire A Scott, Shefali Rajpopat, Wei-Li Di
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