Showing results (11-20 of 21) with videos related to
Sort By:
Pageof 3
Nature|April 23, 2010
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effectMin Gao, Richard E Nettles, Makonen Belema, et al.Bioorganic & Medicinal Chemistry|May 23, 2022
Scaffold modifications to the 4-(4,4-dimethylpiperidinyl) 2,6-dimethylpyridinyl class of HIV-1 allosteric integrase inhibitorsKyle Parcella, Manoj Patel, Yong Tu, et al.Bioorganic & Medicinal Chemistry Letters|September 11, 2012
HCV NS5A replication complex inhibitors. Part 2: investigation of stilbene prolinamidesDenis R St Laurent, Makonen Belema, Min Gao, et al.Journal of Medicinal Chemistry|January 21, 2014
Hepatitis C virus NS5A replication complex inhibitors. Part 6: Discovery of a novel and highly potent biarylimidazole chemotype with inhibitory activity toward genotypes 1a and 1b repliconsMakonen Belema, Van N Nguyen, Jeffrey L Romine, et al.Nature|November 5, 2015
Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5AJin-Hua Sun, Donald R O'Boyle, Robert A Fridell, et al.Bioorganic & Medicinal Chemistry Letters|January 1, 2013
HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologiesOmar D Lopez, Van N Nguyen, Denis R St Laurent, et al.Journal of Medicinal Chemistry|April 12, 2013
HCV NS5A replication complex inhibitors. Part 4. Optimization for genotype 1a replicon inhibitory activityDenis R St Laurent, Michael H Serrano-Wu, Makonen Belema, et al.The Journal of Organic Chemistry|September 7, 2017
Development of the Large-Scale Synthesis of Tetrahydropyran Glycine, a Precursor to the HCV NS5A Inhibitor BMS-986097Arvind Mathur, Bei Wang, Daniel Smith, et al.Journal of Medicinal Chemistry|January 31, 2023
Potent Long-Acting Inhibitors Targeting the HIV-1 Capsid Based on a Versatile Quinazolin-4-one ScaffoldEric P Gillis, Kyle Parcella, Michael Bowsher, et al.ACS Medicinal Chemistry Letters|June 16, 2022
Discovery and Preclinical Profiling of GSK3839919, a Potent HIV-1 Allosteric Integrase InhibitorKyle Parcella, Tao Wang, Kyle Eastman, et al.Pageof 3