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Pharmaceutical Research
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June 24, 2003
Prediction of in vivo tissue distribution from in vitro data. 2. Influence of albumin diffusion from tissue pieces during an in vitro incubation on estimated tissue-to-unbound plasma partition coefficients (Kpu)
Peter Ballard, Philip A Arundel, David E Leahy, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 19, 2011
Measurement of binding of basic drugs to acidic phospholipids using surface plasmon resonance and incorporation of the data into mechanistic tissue composition equations to predict steady-state volume of distribution
Helen Small, Iain Gardner, Hannah M Jones, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 21, 2002
Incorporating measures of variability and uncertainty into the prediction of in vivo hepatic clearance from in vitro data
Ivan Nestorov, Ivelina Gueorguieva, Hannah M Jones, et al.
Journal of Pharmaceutical Sciences
|
October 23, 2023
Target Reserve and Turnover Parameters Determine Rightward Shift of Enalaprilat Potency From its Binding Affinity to the Angiotensin Converting Enzyme
Van Anh Nguyen, Li Zhang, Leonid Kagan, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
March 22, 2006
Optimal design for multivariate response pharmacokinetic models
Ivelina Gueorguieva, Leon Aarons, Kayode Ogungbenro, et al.
Biochemical Pharmacology
|
August 10, 2019
Hepatic clearance concepts and misconceptions: Why the well-stirred model is still used even though it is not physiologic reality?
K Sandy Pang, Yi Rang Han, Keumhan Noh, et al.
Nature Reviews. Drug Discovery
|
September 9, 2020
Phase 0/microdosing approaches: time for mainstream application in drug development?
Tal Burt, Graeme Young, Wooin Lee, et al.
Journal of Pharmaceutical Sciences
|
June 24, 2018
Past, Present, and Future of Bioequivalence: Improving Assessment and Extrapolation of Therapeutic Equivalence for Oral Drug Products
Rodrigo Cristofoletti, Malcolm Rowland, Lawrence J Lesko, et al.
AIDS Research and Human Retroviruses
|
October 31, 2003
Protein binding in antiretroviral therapies
Marta Boffito, David J Back, Terrence F Blaschke, et al.
Drug Discovery Today
|
June 22, 2018
Importance of target-mediated drug disposition for small molecules
Dennis A Smith, Robert A B van Waterschoot, Neil J Parrott, et al.
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of 6
Search research articles
Search
Showing results (31-40 of 53) with videos related to
Sort By:
Page
of 6
Pharmaceutical Research
|
June 24, 2003
Prediction of in vivo tissue distribution from in vitro data. 2. Influence of albumin diffusion from tissue pieces during an in vitro incubation on estimated tissue-to-unbound plasma partition coefficients (Kpu)
Peter Ballard, Philip A Arundel, David E Leahy, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 19, 2011
Measurement of binding of basic drugs to acidic phospholipids using surface plasmon resonance and incorporation of the data into mechanistic tissue composition equations to predict steady-state volume of distribution
Helen Small, Iain Gardner, Hannah M Jones, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 21, 2002
Incorporating measures of variability and uncertainty into the prediction of in vivo hepatic clearance from in vitro data
Ivan Nestorov, Ivelina Gueorguieva, Hannah M Jones, et al.
Journal of Pharmaceutical Sciences
|
October 23, 2023
Target Reserve and Turnover Parameters Determine Rightward Shift of Enalaprilat Potency From its Binding Affinity to the Angiotensin Converting Enzyme
Van Anh Nguyen, Li Zhang, Leonid Kagan, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
March 22, 2006
Optimal design for multivariate response pharmacokinetic models
Ivelina Gueorguieva, Leon Aarons, Kayode Ogungbenro, et al.
Biochemical Pharmacology
|
August 10, 2019
Hepatic clearance concepts and misconceptions: Why the well-stirred model is still used even though it is not physiologic reality?
K Sandy Pang, Yi Rang Han, Keumhan Noh, et al.
Nature Reviews. Drug Discovery
|
September 9, 2020
Phase 0/microdosing approaches: time for mainstream application in drug development?
Tal Burt, Graeme Young, Wooin Lee, et al.
Journal of Pharmaceutical Sciences
|
June 24, 2018
Past, Present, and Future of Bioequivalence: Improving Assessment and Extrapolation of Therapeutic Equivalence for Oral Drug Products
Rodrigo Cristofoletti, Malcolm Rowland, Lawrence J Lesko, et al.
AIDS Research and Human Retroviruses
|
October 31, 2003
Protein binding in antiretroviral therapies
Marta Boffito, David J Back, Terrence F Blaschke, et al.
Drug Discovery Today
|
June 22, 2018
Importance of target-mediated drug disposition for small molecules
Dennis A Smith, Robert A B van Waterschoot, Neil J Parrott, et al.
Page
of 6