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Pharmaceutical Research
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November 27, 2012
Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential
Michael Gertz, Catherine M Cartwright, Michael J Hobbs, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
November 26, 2004
Development of a whole body physiologically based model to characterise the pharmacokinetics of benzodiazepines. 1: Estimation of rat tissue-plasma partition ratios
Ivelina Gueorguieva, Ivan A Nestorov, Susan Murby, et al.
Clinical Pharmacology and Therapeutics
|
September 6, 2006
Use of microdosing to predict pharmacokinetics at the therapeutic dose: experience with 5 drugs
Graham Lappin, Wilhelm Kuhnz, Roeline Jochemsen, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
March 24, 2010
Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability
Graham Lappin, Yoko Shishikura, Roeline Jochemsen, et al.
Nature Reviews. Drug Discovery
|
July 2, 2011
Bridging the efficacy-effectiveness gap: a regulator's perspective on addressing variability of drug response
Hans-Georg Eichler, Eric Abadie, Alasdair Breckenridge, et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
|
August 9, 2007
Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations
Simon R Clark, Catherine J McMahon, Iva Gueorguieva, et al.
British Journal of Clinical Pharmacology
|
September 19, 2007
Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage
Ivelina Gueorguieva, Simon R Clark, Catherine J McMahon, et al.
Journal of Pharmaceutical Sciences
|
August 23, 2012
Impact of the pharmaceutical sciences on health care: a reflection over the past 50 years
Malcolm Rowland, Christian R Noe, Dennis A Smith, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
May 5, 2011
Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers
Graham Lappin, Yoko Shishikura, Roeline Jochemsen, et al.
Journal of Pharmaceutical Sciences
|
May 5, 2011
PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: comparative assessement of prediction methods of human clearance
Barbara J Ring, Jenny Y Chien, Kimberly K Adkison, et al.
Page
of 6
Search research articles
Search
Showing results (41-50 of 53) with videos related to
Sort By:
Page
of 6
Pharmaceutical Research
|
November 27, 2012
Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential
Michael Gertz, Catherine M Cartwright, Michael J Hobbs, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
November 26, 2004
Development of a whole body physiologically based model to characterise the pharmacokinetics of benzodiazepines. 1: Estimation of rat tissue-plasma partition ratios
Ivelina Gueorguieva, Ivan A Nestorov, Susan Murby, et al.
Clinical Pharmacology and Therapeutics
|
September 6, 2006
Use of microdosing to predict pharmacokinetics at the therapeutic dose: experience with 5 drugs
Graham Lappin, Wilhelm Kuhnz, Roeline Jochemsen, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
March 24, 2010
Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability
Graham Lappin, Yoko Shishikura, Roeline Jochemsen, et al.
Nature Reviews. Drug Discovery
|
July 2, 2011
Bridging the efficacy-effectiveness gap: a regulator's perspective on addressing variability of drug response
Hans-Georg Eichler, Eric Abadie, Alasdair Breckenridge, et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
|
August 9, 2007
Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations
Simon R Clark, Catherine J McMahon, Iva Gueorguieva, et al.
British Journal of Clinical Pharmacology
|
September 19, 2007
Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage
Ivelina Gueorguieva, Simon R Clark, Catherine J McMahon, et al.
Journal of Pharmaceutical Sciences
|
August 23, 2012
Impact of the pharmaceutical sciences on health care: a reflection over the past 50 years
Malcolm Rowland, Christian R Noe, Dennis A Smith, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
May 5, 2011
Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers
Graham Lappin, Yoko Shishikura, Roeline Jochemsen, et al.
Journal of Pharmaceutical Sciences
|
May 5, 2011
PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: comparative assessement of prediction methods of human clearance
Barbara J Ring, Jenny Y Chien, Kimberly K Adkison, et al.
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of 6