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Manoj K Rathinaswamy

Showing results (1-10 of 17) with videos related to

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Advances in Biological Regulation|October 16, 2019
Class I phosphoinositide 3-kinase (PI3K) regulatory subunits and their roles in signaling and diseaseManoj K Rathinaswamy, John E Burke
The Journal of Biological Chemistry|May 19, 2017
Molecular mechanism of activation of class IA phosphoinositide 3-kinases (PI3Ks) by membrane-localized HRasBraden D Siempelkamp, Manoj K Rathinaswamy, Meredith L Jenkins, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 11, 2018
Conformational sampling of membranes by Akt controls its activation and inactivationIva Lučić, Manoj K Rathinaswamy, Linda Truebestein, et al.
Nature Communications|January 12, 2023
Oncogenic mutations of PIK3CA lead to increased membrane recruitment driven by reorientation of the ABD, p85 and C-terminusMeredith L Jenkins, Harish Ranga-Prasad, Matthew A H Parson, et al.
Structure (London, England : 1993)|December 14, 2019
Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-KinasesGillian L Dornan, Jordan T B Stariha, Manoj K Rathinaswamy, et al.
Structure (London, England : 1993)|August 4, 2021
HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinasesManoj K Rathinaswamy, Kaelin D Fleming, Udit Dalwadi, et al.
Cell Chemical Biology|October 17, 2017
Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP StatesDaniel R Gentile, Manoj K Rathinaswamy, Meredith L Jenkins, et al.
Elife|March 4, 2021
Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitorsManoj K Rathinaswamy, Zied Gaieb, Kaelin D Fleming, et al.
Blood Vessels, Thrombosis & Hemostasis|August 6, 2025
Structural basis of MPL activation by thrombopoietinAmirhossein Mafi, Matthew Bratkowski, Jiefei Geng, et al.
Science Advances|August 28, 2021
Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activationManoj K Rathinaswamy, Udit Dalwadi, Kaelin D Fleming, et al.
Pageof 2

Showing results (1-10 of 17) with videos related to

Sort By:
Pageof 2
Advances in Biological Regulation|October 16, 2019
Class I phosphoinositide 3-kinase (PI3K) regulatory subunits and their roles in signaling and diseaseManoj K Rathinaswamy, John E Burke
The Journal of Biological Chemistry|May 19, 2017
Molecular mechanism of activation of class IA phosphoinositide 3-kinases (PI3Ks) by membrane-localized HRasBraden D Siempelkamp, Manoj K Rathinaswamy, Meredith L Jenkins, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 11, 2018
Conformational sampling of membranes by Akt controls its activation and inactivationIva Lučić, Manoj K Rathinaswamy, Linda Truebestein, et al.
Nature Communications|January 12, 2023
Oncogenic mutations of PIK3CA lead to increased membrane recruitment driven by reorientation of the ABD, p85 and C-terminusMeredith L Jenkins, Harish Ranga-Prasad, Matthew A H Parson, et al.
Structure (London, England : 1993)|December 14, 2019
Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-KinasesGillian L Dornan, Jordan T B Stariha, Manoj K Rathinaswamy, et al.
Structure (London, England : 1993)|August 4, 2021
HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinasesManoj K Rathinaswamy, Kaelin D Fleming, Udit Dalwadi, et al.
Cell Chemical Biology|October 17, 2017
Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP StatesDaniel R Gentile, Manoj K Rathinaswamy, Meredith L Jenkins, et al.
Elife|March 4, 2021
Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitorsManoj K Rathinaswamy, Zied Gaieb, Kaelin D Fleming, et al.
Blood Vessels, Thrombosis & Hemostasis|August 6, 2025
Structural basis of MPL activation by thrombopoietinAmirhossein Mafi, Matthew Bratkowski, Jiefei Geng, et al.
Science Advances|August 28, 2021
Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activationManoj K Rathinaswamy, Udit Dalwadi, Kaelin D Fleming, et al.
Pageof 2