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International Journal of Molecular Sciences|December 10, 2020
Altered PPARγ Expression Promotes Myelin-Induced Foam Cell Formation in Macrophages in Multiple SclerosisElien Wouters, Elien Grajchen, Winde Jorissen, et al.Journal of Neuroinflammation|July 5, 2021
Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophagesTess Dierckx, Mansour Haidar, Elien Grajchen, et al.Proceedings of the National Academy of Sciences of the United States of America|November 7, 2022
Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiationTess Dierckx, Sam Vanherle, Mansour Haidar, et al.Journal of Neuroinflammation|July 29, 2020
CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammationElien Grajchen, Elien Wouters, Britt van de Haterd, et al.Journal of Extracellular Vesicles|March 12, 2021
Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasisBram Van den Broek, Isabel Pintelon, Ibrahim Hamad, et al.Proceedings of the National Academy of Sciences of the United States of America|September 5, 2023
Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelinationAida V Garcia Corrales, Sanne G S Verberk, Mansour Haidar, et al.Cell Reports|November 9, 2022
The ApoA-I mimetic peptide 5A enhances remyelination by promoting clearance and degradation of myelin debrisSam Vanherle, Winde Jorissen, Tess Dierckx, et al.Nature Communications|August 29, 2025
UBE3A promotes foam cell formation and counters remyelination by targeting ABCA1 for proteasomal degradationMelanie Loix, Sam Vanherle, Laura Bolkaerts, et al.Human Mutation|February 2, 2017
Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel MutationsAndoni Echaniz-Laguna, Thomas Geuens, Philippe Petiot, et al.Journal of Extracellular Vesicles|December 21, 2023
Extracellular vesicle-associated cholesterol supports the regenerative functions of macrophages in the brainSam Vanherle, Jeroen Guns, Melanie Loix, et al.Pageof 3