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Pharmaceutical Research|July 10, 2015
Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS)Manthena V Varma, Stefanus J Steyn, Charlotte Allerton, et al.
CPT: Pharmacometrics & Systems Pharmacology|August 18, 2019
Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein InductionShinji Yamazaki, Chester Costales, Sarah Lazzaro, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 10, 2017
Quantitative Prediction of Human Renal Clearance and Drug-Drug Interactions of Organic Anion Transporter Substrates Using In Vitro Transport Data: A Relative Activity Factor ApproachSumathy Mathialagan, Mary A Piotrowski, David A Tess, et al.
Pharmaceutical Research|September 14, 2016
Projecting ADME Behavior and Drug-Drug Interactions in Early Discovery and Development: Application of the Extended Clearance Classification SystemAyman F El-Kattan, Manthena V Varma, Stefan J Steyn, et al.
Current Topics in Medicinal Chemistry|April 13, 2013
High specificity in response of the sodium-dependent multivitamin transporter to derivatives of pantothenic acidSrinivas Reddy Chirapu, Charles J Rotter, Emily L Miller, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 26, 2013
A perspective on the prediction of drug pharmacokinetics and disposition in drug research and developmentLi Di, Bo Feng, Theunis C Goosen, et al.
Molecular Pharmaceutics|September 27, 2013
Quantitative prediction of renal transporter-mediated clinical drug-drug interactionsBo Feng, Susan Hurst, Yasong Lu, et al.
Biopharmaceutics & Drug Disposition|September 3, 2013
Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatinYi-an Bi, Xi Qiu, Charles J Rotter, et al.
Current Drug Metabolism|December 30, 2010
Targeting intestinal transporters for optimizing oral drug absorptionManthena V Varma, Catherine M Ambler, Mohammad Ullah, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 27, 2015
Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and HumansJennifer Q Dong, Manthena V Varma, Angela Wolford, et al.
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