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Current Topics in Medicinal Chemistry|April 13, 2013
Intestinal targeting of drugs: rational design approaches and challengesKevin J Filipski, Manthena V Varma, Ayman F El-Kattan, et al.Expert Opinion on Drug Metabolism & Toxicology|January 22, 2013
Model-based approaches to predict drug-drug interactions associated with hepatic uptake transporters: preclinical, clinical and beyondHugh A Barton, Yurong Lai, Theunis C Goosen, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 19, 2016
The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide-Mediated Hepatic Clearance and May Potentiate Statin-Induced MyopathyHeather Eng, Renato J Scialis, Charles J Rotter, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 9, 2018
Simultaneous Assessment of Transporter-Mediated Drug-Drug Interactions Using a Probe Drug Cocktail in Cynomolgus MonkeyRachel E Kosa, Sarah Lazzaro, Yi-An Bi, et al.Molecular Pharmaceutics|June 30, 2011
pH-sensitive interaction of HMG-CoA reductase inhibitors (statins) with organic anion transporting polypeptide 2B1Manthena V Varma, Charles J Rotter, Jonathan Chupka, et al.Molecular Pharmaceutics|April 12, 2012
pH-Dependent solubility and permeability criteria for provisional biopharmaceutics classification (BCS and BDDCS) in early drug discoveryManthena V Varma, Iain Gardner, Stefanus J Steyn, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|May 2, 2013
Elucidation of the biochemical basis for a clinical drug-drug interaction between atorvastatin and 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methyl benzoic acid (CP-778875), a subtype selective agonist of the peroxisome proliferator-activated receptor alphaAmit S Kalgutkar, Danny Chen, Manthena V Varma, et al.Medchemcomm|November 8, 2012
Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance()Arthur C Rand, Siegfried S F Leung, Heather Eng, et al.Journal of Pharmaceutical Sciences|July 19, 2011
Development of a new permeability assay using low-efflux MDCKII cellsLi Di, Carrie Whitney-Pickett, John P Umland, et al.Journal of Medicinal Chemistry|August 19, 2020
Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver TargetingKim Huard, Aaron C Smith, Gregg Cappon, et al.Pageof 4