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Journal of Medicinal Chemistry|July 25, 2003
Synthesis and structure-activity relationship of a new series of COX-2 selective inhibitors: 1,5-diarylimidazolesCarmen Almansa, José Alfón, Alberto F de Arriba, et al.The Journal of Pharmacology and Experimental Therapeutics|October 25, 2013
Modulation of peripheral μ-opioid analgesia by σ1 receptorsCristina Sánchez-Fernández, Ángeles Montilla-García, Rafael González-Cano, et al.European Journal of Pharmacology|May 2, 2013
Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effectsAlba Vidal-Torres, Beatriz de la Puente, Maria Rocasalbas, et al.Journal of Medicinal Chemistry|July 13, 2012
Synthesis and biological evaluation of the 1-arylpyrazole class of σ(1) receptor antagonists: identification of 4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862)José Luis Díaz, Rosa Cuberes, Joana Berrocal, et al.Acta Pharmaceutica Sinica. B|February 23, 2023
Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioidsAlba Vidal-Torres, Begoña Fernández-Pastor, Mónica García, et al.Journal of Medicinal Chemistry|October 16, 2020
Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ1 Receptor Antagonist Clinical Candidate for the Treatment of PainMónica García, Marina Virgili, Mònica Alonso, et al.Journal of Medicinal Chemistry|April 9, 2013
Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligandsJosé Luis Díaz, Ute Christmann, Ariadna Fernández, et al.Pageof 8