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Bioorganic Chemistry|April 2, 2023
Rational design, synthesis and biological evaluation of benzo[d]isoxazole derivatives as potent BET bivalent inhibitors for potential treatment of prostate cancerJunhua Li, Run Zhu, Xiaoxi Zhuang, et al.Bioorganic Chemistry|November 29, 2019
Discovery and optimization of novel N-benzyl-3,6-dimethylbenzo[d]isoxazol-5-amine derivatives as potent and selective TRIM24 bromodomain inhibitors with potential anti-cancer activitiesQingqing Hu, Chao Wang, Qiuping Xiang, et al.European Journal of Medicinal Chemistry|April 6, 2022
Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitorsQiuping Xiang, Guolong Luo, Cheng Zhang, et al.European Journal of Medicinal Chemistry|May 15, 2018
Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancerXiaoqian Xue, Yan Zhang, Chao Wang, et al.Journal of Medicinal Chemistry|March 25, 2022
Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) InhibitorsJunhua Li, Cheng Zhang, Hongrui Xu, et al.Iscience|March 30, 2026
New selective and allosteric FLT3 inhibitors show efficacy against resistant acute myeloid leukemia cellsShuai-Shuai Ge, Qiao-Cheng Qiu, Jingsheng Hua, et al.Journal of Medicinal Chemistry|March 24, 2018
Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC)Maofeng Zhang, Yan Zhang, Ming Song, et al.Pageof 5