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Experimental Hematology|January 9, 2023
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanismsAndrea Arena, Maria Anele Romeo, Rossella Benedetti, et al.
Biomedicines|April 23, 2022
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma CellsAndrea Arena, Maria Anele Romeo, Rossella Benedetti, et al.
Biochemical and Biophysical Research Communications|May 8, 2022
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cellsAndrea Arena, Maria Anele Romeo, Rossella Benedetti, et al.
Cell Death Discovery|April 10, 2025
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cellsRossella Benedetti, Michele Di Crosta, Maria Saveria Gilardini Montani, et al.
Current Issues in Molecular Biology|March 27, 2024
5-AZA Upregulates SOCS3 and PTPN6/SHP1, Inhibiting STAT3 and Potentiating the Effects of AG490 against Primary Effusion Lymphoma CellsMichele Di Crosta, Andrea Arena, Rossella Benedetti, et al.
Journal of Medical Virology|September 5, 2002
Human herpesvirus 6 and multiple sclerosis: a study of T cell cross-reactivity to viral and myelin basic protein antigensMara Cirone, Laura Cuomo, Claudia Zompetta, et al.
Journal of Experimental & Clinical Cancer Research : CR|November 29, 2017
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell deathMarisa Granato, Maria Saveria Gilardini Montani, Roberta Santarelli, et al.
Viruses|December 28, 2018
Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1Marisa Granato, Maria Saveria Gilardini Montani, Camilla Angiolillo, et al.
Oncotarget|December 1, 2016
Hyperglycemia triggers HIPK2 protein degradationSilvia Baldari, Alessia Garufi, Marisa Granato, et al.
Biomolecules|March 7, 2020
Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 DegradationAlessia Garufi, Giulia Federici, Maria Saveria Gilardini Montani, et al.
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