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Marc C Nicklaus

Showing results (51-60 of 91) with videos related to

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Medchemcomm|January 17, 2019
Probing the <i>hras</i>-1<sup>Y</sup> i-motif with small moleculesSara N Journey, Stephanie L Alden, Will M Hewitt, et al.
Bioorganic & Medicinal Chemistry|April 24, 2013
Inhibitors for the hepatitis C virus RNA polymerase explored by SAR with advanced machine learning methodsIwona E Weidlich, Igor V Filippov, Jodian Brown, et al.
Frontiers in Oncology|May 14, 2023
Virtual screening of ultra-large chemical libraries identifies cell-permeable small-molecule inhibitors of a "non-druggable" target, STAT3 N-terminal domainPedro Andrade Bonilla, Cody L Hoop, Karen Stefanisko, et al.
Journal of Medicinal Chemistry|September 17, 2004
Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)Hirokazu Tamamura, Dina M Sigano, Nancy E Lewin, et al.
Journal of Medicinal Chemistry|September 2, 2005
Conformationally constrained analogues of diacylglycerol (DAG). 25. Exploration of the sn-1 and sn-2 carbonyl functionality reveals the essential role of the sn-1 carbonyl at the lipid interface in the binding of DAG-lactones to protein kinase CJi-Hye Kang, Megan L Peach, Yongmei Pu, et al.
Carcinogenesis|October 20, 2005
Evidence that sequence homologous region in LRAT-like proteins possesses anti-proliferative activity and DNA binding properties: translational implications and mechanism of actionDenise Perry Simmons, Megan L Peach, Jonathan R Friedman, et al.
Journal of the American Chemical Society|June 19, 2008
Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid stateJoseph J Barchi, Rajeshri G Karki, Marc C Nicklaus, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Acylsulfonamide-containing PTP1B inhibitors designed to mimic an enzyme-bound water of hydrationDing-Guo Liu, Yang Gao, Johannes H Voigt, et al.
Chemistry & Biodiversity|December 29, 2006
Utilization of a common pathway for the synthesis of high affinity macrocyclic Grb2 SH2 domain-binding peptide mimetics that differ in the configuration at one ring junctionZhen-Dan Shi, Rajeshri G Karki, Karen M Worthy, et al.
Journal of Medicinal Chemistry|February 10, 2009
Directed discovery of agents targeting the Met tyrosine kinase domain by virtual screeningMegan L Peach, Nelly Tan, Sarah J Choyke, et al.
Pageof 10

Showing results (51-60 of 91) with videos related to

Sort By:
Pageof 10
Medchemcomm|January 17, 2019
Probing the <i>hras</i>-1<sup>Y</sup> i-motif with small moleculesSara N Journey, Stephanie L Alden, Will M Hewitt, et al.
Bioorganic & Medicinal Chemistry|April 24, 2013
Inhibitors for the hepatitis C virus RNA polymerase explored by SAR with advanced machine learning methodsIwona E Weidlich, Igor V Filippov, Jodian Brown, et al.
Frontiers in Oncology|May 14, 2023
Virtual screening of ultra-large chemical libraries identifies cell-permeable small-molecule inhibitors of a "non-druggable" target, STAT3 N-terminal domainPedro Andrade Bonilla, Cody L Hoop, Karen Stefanisko, et al.
Journal of Medicinal Chemistry|September 17, 2004
Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)Hirokazu Tamamura, Dina M Sigano, Nancy E Lewin, et al.
Journal of Medicinal Chemistry|September 2, 2005
Conformationally constrained analogues of diacylglycerol (DAG). 25. Exploration of the sn-1 and sn-2 carbonyl functionality reveals the essential role of the sn-1 carbonyl at the lipid interface in the binding of DAG-lactones to protein kinase CJi-Hye Kang, Megan L Peach, Yongmei Pu, et al.
Carcinogenesis|October 20, 2005
Evidence that sequence homologous region in LRAT-like proteins possesses anti-proliferative activity and DNA binding properties: translational implications and mechanism of actionDenise Perry Simmons, Megan L Peach, Jonathan R Friedman, et al.
Journal of the American Chemical Society|June 19, 2008
Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid stateJoseph J Barchi, Rajeshri G Karki, Marc C Nicklaus, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Acylsulfonamide-containing PTP1B inhibitors designed to mimic an enzyme-bound water of hydrationDing-Guo Liu, Yang Gao, Johannes H Voigt, et al.
Chemistry & Biodiversity|December 29, 2006
Utilization of a common pathway for the synthesis of high affinity macrocyclic Grb2 SH2 domain-binding peptide mimetics that differ in the configuration at one ring junctionZhen-Dan Shi, Rajeshri G Karki, Karen M Worthy, et al.
Journal of Medicinal Chemistry|February 10, 2009
Directed discovery of agents targeting the Met tyrosine kinase domain by virtual screeningMegan L Peach, Nelly Tan, Sarah J Choyke, et al.
Pageof 10