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Proceedings of the National Academy of Sciences of the United States of America|July 29, 2020
Cumulative mechanism of several major imatinib-resistant mutations in Abl kinaseMarc Hoemberger, Warintra Pitsawong, Dorothee KernProceedings of the National Academy of Sciences of the United States of America|June 27, 2019
Allosteric modulation of a human protein kinase with monobodiesAdelajda Zorba, Vy Nguyen, Akiko Koide, et al.Nature Catalysis|March 12, 2020
Probing the Transition State in Enzyme Catalysis by High-Pressure NMR DynamicsJohn B Stiller, S Jordan Kerns, Marc Hoemberger, et al.Nature|March 23, 2023
From primordial clocks to circadian oscillatorsWarintra Pitsawong, Ricardo A P Pádua, Timothy Grant, et al.Science (New York, N.Y.)|December 24, 2016
Evolutionary drivers of thermoadaptation in enzyme catalysisVy Nguyen, Christopher Wilson, Marc Hoemberger, et al.Bioorganic & Medicinal Chemistry Letters|January 18, 2022
Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitorsBin Ma, Claire M Metrick, Chungang Gu, et al.Journal of Medicinal Chemistry|April 7, 2026
Leveraging Kinase Drugs for Neurosciences: Discovery of Selective, CNS-Penetrant Reversible Bruton's Tyrosine Kinase Inhibitors as Therapeutics for NeuroinflammationBrian T Hopkins, Isaac E Marx, Harlod George Vandeveer, et al.Journal of Medicinal Chemistry|November 4, 2021
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple SclerosisBrian T Hopkins, Eris Bame, Bekim Bajrami, et al.Journal of Medicinal Chemistry|May 7, 2024
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple SclerosisMartin K Himmelbauer, Bekim Bajrami, Rebecca Basile, et al.Pageof 1