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Biochimie|April 15, 2018
Chemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3β,5α-diol (OCDO), a tumor promoter and cholesterol metaboliteMarc Poirot, Regis Soules, Arnaud Mallinger, et al.Journal of Lipid Research|May 17, 2018
Extracellular vesicles: lipids as key components of their biogenesis and functionsMichel Record, Sandrine Silvente-Poirot, Marc Poirot, et al.Biochemical Pharmacology|May 6, 2026
Pharmacological targeting of cholesterol biosynthesis in cancer: Sterol intermediates, oxysterols, and sterol flux rewiringPhilippe de Médina, Julio Buñay, Silia Ayadi, et al.Autophagy|September 5, 2022
Targeting NR1H/liver X receptor with dendrogenin A differentiates tumor cells to activate a new secretory pathway releasing immunogenic anti-tumor vesicles enriched in LC3-II-associated exosomesPhilippe de Medina, Julio Bunay, Marc Poirot, et al.Ageing Research Reviews|November 28, 2025
Liver X receptors and the hallmarks of aging: From molecular mechanisms to therapeutic opportunitiesMarc Poirot, Julio Buñay, Silia Ayadi, et al.Breast Cancer Research : BCR|February 7, 2006
Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathwaysFlorence Dalenc, Claire Giamarchi, Mélissa Petit, et al.Medical Physics|May 3, 2013
Improved realism of hybrid mouse models may not be sufficient to generate reference dosimetric dataThibault Mauxion, Jacques Barbet, Jérôme Suhard, et al.Journal of Medicinal Chemistry|October 14, 2009
Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseasesPhilippe de Medina, Michael R Paillasse, Bruno Payré, et al.Proceedings of the National Academy of Sciences of the United States of America|July 10, 2010
Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligandsPhilippe de Medina, Michael R Paillasse, Gregory Segala, et al.Seminars in Cancer Biology|March 16, 2026
Oxysterols at the Crossroads of Cholesterol Metabolism and CancerJulio Buñay, Silia Ayadi, Chloe Gressein, et al.Pageof 9