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Bioorganic & Medicinal Chemistry Letters|April 2, 2013
Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoformSteven T Staben, Chudi Ndubaku, Nicole Blaquiere, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349Zhonghua Pei, Elizabeth Blackwood, Lichuan Liu, et al.Journal of Medicinal Chemistry|May 27, 2016
Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical DevelopmentJames F Blake, Michael Burkard, Jocelyn Chan, et al.Molecular Cancer Therapeutics|June 6, 2022
Nonclinical Efficacy and Safety of CX-2029, an Anti-CD71 Probody-Drug ConjugateShweta Singh, Laura Serwer, Amy DuPage, et al.Nature Chemical Biology|August 2, 2016
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibitionAaron Boudreau, Hans E Purkey, Anna Hitz, et al.Nature Genetics|February 26, 2004
Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genomeAnnette L Parks, Kevin R Cook, Marcia Belvin, et al.Pageof 6