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Journal of the American Chemical Society
|
December 13, 2017
Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition
Samuel E Dalton, Lars Dittus, Daniel A Thomas, et al.
ACS Chemical Biology
|
February 11, 2016
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors
Susan Klaeger, Bjoern Gohlke, Jessica Perrin, et al.
Nature Protocols
|
September 18, 2015
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry
Holger Franken, Toby Mathieson, Dorothee Childs, et al.
ACS Chemical Biology
|
December 24, 2015
Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle
Andrew N Billin, Marcus Bantscheff, Gerard Drewes, et al.
Nature Chemical Biology
|
September 27, 2016
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat
Isabelle Becher, Thilo Werner, Carola Doce, et al.
ACS Chemical Biology
|
August 5, 2011
Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons
Nigel Ramsden, Jessica Perrin, Zhao Ren, et al.
Acta Neuropathologica
|
January 14, 2017
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo
Peng Wang, Gerard Joberty, Arjan Buist, et al.
ACS Chemical Biology
|
February 27, 2019
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding
Christopher P Tinworth, Hannah Lithgow, Lars Dittus, et al.
Nature Communications
|
November 5, 2016
Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
Julianty Frost, Carles Galdeano, Pedro Soares, et al.
Molecular Systems Biology
|
March 7, 2024
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition
Mira L Burtscher, Stephan Gade, Martin Garrido-Rodriguez, et al.
Page
of 12
Search research articles
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Showing results (61-70 of 120) with videos related to
Sort By:
Page
of 12
Journal of the American Chemical Society
|
December 13, 2017
Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition
Samuel E Dalton, Lars Dittus, Daniel A Thomas, et al.
ACS Chemical Biology
|
February 11, 2016
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors
Susan Klaeger, Bjoern Gohlke, Jessica Perrin, et al.
Nature Protocols
|
September 18, 2015
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry
Holger Franken, Toby Mathieson, Dorothee Childs, et al.
ACS Chemical Biology
|
December 24, 2015
Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle
Andrew N Billin, Marcus Bantscheff, Gerard Drewes, et al.
Nature Chemical Biology
|
September 27, 2016
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat
Isabelle Becher, Thilo Werner, Carola Doce, et al.
ACS Chemical Biology
|
August 5, 2011
Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons
Nigel Ramsden, Jessica Perrin, Zhao Ren, et al.
Acta Neuropathologica
|
January 14, 2017
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo
Peng Wang, Gerard Joberty, Arjan Buist, et al.
ACS Chemical Biology
|
February 27, 2019
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding
Christopher P Tinworth, Hannah Lithgow, Lars Dittus, et al.
Nature Communications
|
November 5, 2016
Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
Julianty Frost, Carles Galdeano, Pedro Soares, et al.
Molecular Systems Biology
|
March 7, 2024
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition
Mira L Burtscher, Stephan Gade, Martin Garrido-Rodriguez, et al.
Page
of 12