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Biorxiv : the Preprint Server for Biology|October 4, 2023
Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancerLoretah Chibaya, Christina F Lusi, Kelly D DeMarco, et al.Molecular Cancer Therapeutics|March 26, 2026
Tumor Homing Nanoparticle Immunotherapy for Acute Clearance and Mitigation of T-cell Exhaustion in Humanized High-Risk NeuroblastomaGriffin I Kane, Miranda B Diaz-Infante, Kim Wigglesworth, et al.Cancer Discovery|October 24, 2025
P21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by senolytic therapyLin Zhou, Kelly D DeMarco, Katherine C Murphy, et al.Cell|April 3, 2020
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas CancerMarcus Ruscetti, John P Morris, Riccardo Mezzadra, et al.Science Translational Medicine|August 28, 2024
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancerLoretah Chibaya, Kelly D DeMarco, Christina F Lusi, et al.Science (New York, N.Y.)|December 22, 2018
NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combinationMarcus Ruscetti, Josef Leibold, Matthew J Bott, et al.Nature Cancer|May 4, 2023
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillanceLoretah Chibaya, Katherine C Murphy, Kelly D DeMarco, et al.Biorxiv : the Preprint Server for Biology|June 12, 2025
Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesisNikita Bhalerao, Yamini Ogoti, Jessica Peura, et al.Proceedings of the National Academy of Sciences of the United States of America|September 22, 2025
PPT1 is a negative regulator of STING signaling in cancer cells and its inhibition reactivates immune surveillance in cold tumorsShreya R Chowdhury, Chaitanya N Parikh, Arshia N Kaur, et al.Nature Communications|June 19, 2026
Multiplexed cytokine and antigen mRNA administration generates durable anti-tumor immunity against pancreatic cancerChaitanya N Parikh, Kelly D DeMarco, Nikita Bhalerao, et al.Pageof 4